Evaluation of resynchronization of contractile function following biventricular pacing using colour tissue Doppler imaging

Bax, J. J., Marwick, T., van Erven, L., Molhoek, S., Adriaansche, C., de Melker, R., Voogd, P., van der Wall, E. and Schalij, M. (2002). Evaluation of resynchronization of contractile function following biventricular pacing using colour tissue Doppler imaging. In: William Parmley, Abstracte of the 51st Annual Scientific Session of the American College of Cardiology. 51st Annual Scientific Session of the American College of Cardiology, Atlanta GA, United States, (356A-356A). 17–20 March 2002. doi:10.1016/S0735-1097(02)81599-6


Author Bax, J. J.
Marwick, T.
van Erven, L.
Molhoek, S.
Adriaansche, C.
de Melker, R.
Voogd, P.
van der Wall, E.
Schalij, M.
Title of paper Evaluation of resynchronization of contractile function following biventricular pacing using colour tissue Doppler imaging
Conference name 51st Annual Scientific Session of the American College of Cardiology
Conference location Atlanta GA, United States
Conference dates 17–20 March 2002
Proceedings title Abstracte of the 51st Annual Scientific Session of the American College of Cardiology   Check publisher's open access policy
Journal name Journal of the American College of Cardiology   Check publisher's open access policy
Place of Publication San Diego, CA, United States
Publisher Elsevier
Publication Year 2002
Sub-type Published abstract
DOI 10.1016/S0735-1097(02)81599-6
Open Access Status Not Open Access
ISSN 0735-1097
Editor William Parmley
Volume 39
Issue Supplement 2
Start page 356A
End page 356A
Total pages 1
Language eng
Abstract/Summary Biventdcular (BV) pacing is evaluated as an alternative treatment for patients with dilated cardiomyppathy (both ischemic and non-ischemic) and end-stage heart failure. Colour tissue Doppler imaging using echocardiography allows noninvasive, quantitative assessment of radial motion in the long-axis with measurement of peak systolic velocity timing. The aim of the present study was to evaluate quantitatively, the systolic performance of the left ventricle and the resynchrenization of contraction (before vs after implantation). Patients and methods: 25 patients with dilated cardiomyopathy (11 ischemic), NYHA class III or IV, QRS duration >120 ms received a biventricular pacemaker. Routine 2D echo and colour tissue Doppler imaging were performed before and within 1 week following implantation. LVEF was assessed using the biplane Sampson's method.Peak systolic velocity (PSV) and time to PSV (TPV) were assessed in 4 regions (basal anterior, inferior, lateral and septal). By averaging the TPV from all 4 regions, a synchronization index was dedved from these measurements. Reaults: LVEF improved by 9±9% following pacing; 17 patients improved LVEF 5% or more. The change in PSV in the septal and lateral regions related significantly to the change in LVEF (r=0.74, r=0.62).The change in synchronization index before vs after pacing (as a measurement of REsynchronization) was related to the change in LVEF (y=120x+5.6, r=0.79, P<0,01). Using a change in synchronization of 40, a sensitivity of 76% and a specificity of 100% were obtained to predict improvement of LVEE Conclusion: Colour tissue Doppler imaging allows assessment of resynchronization of contraction following BV pacing and may be used to predict change in LVEE
Subjects 110201 Cardiology (incl. Cardiovascular Diseases)
EX
Keyword Cardiac & Cardiovascular Systems
Q-Index Code EX

 
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Created: Mon, 20 Aug 2007, 03:04:27 EST