Lifetime suicide risk in major depression: sex and age determinants

Blair-West, G. W., Cantor, C. H., Mellsop, G. W. and Eyeson-Annan, M. L. (1999) Lifetime suicide risk in major depression: sex and age determinants. Journal of Affective Disorders, 55 1999: 171-178. doi:10.1016/S0165-0327(99)00004-X

Author Blair-West, G. W.
Cantor, C. H.
Mellsop, G. W.
Eyeson-Annan, M. L.
Title Lifetime suicide risk in major depression: sex and age determinants
Journal name Journal of Affective Disorders   Check publisher's open access policy
ISSN 0165-0327
Publication date 1999-01-01
Sub-type Article (original research)
DOI 10.1016/S0165-0327(99)00004-X
Open Access Status Not yet assessed
Volume 55
Issue 1999
Start page 171
End page 178
Total pages 8
Editor C. Katona
A. S. Akiskal
Place of publication Amsterdam
Publisher Elsevier Science
Language eng
Subject C1
321204 Mental Health
Abstract Background: Recent work has demonstrated that the lifetime suicide risk for patients with DSM IV Major Depression cannot mathematically approximate the accepted figure of 15%. Gender and age significantly affect both the prevalence of major depression and suicide risk, Methods: Gender and age stratified calculations were made on the entire population of the USA in 1994 using a mathematical algorithm. Sex specific corrections for under-reporting were incorporated into the design. Results: The lifetime suicide risks for men and women were 7% and 1%, respectively. The combined risk was 3.4%. The male:female ratio for suicide risk in major depression was 10:1 for youths under 25, and 5.6:1 for adults. Conclusions: Suicide in major depression is predominantly a male problem, although complacency towards female sufferers is to be avoided. Diagnosis of major depression is of limited help in predicting suicide risk compared to case specific factors. The male experience of depression that leads to suicide is often not identified as a legitimate medical complaint by either sufferers or professionals. Increasing help-accessing by males is a priority. Clinical implications: Patients with a history of hospitalisation; comorbidity, especially for substance abuse; and who are male, require greater vigilance for suicide risk. It may be that for males che threshold for diagnosing and treating major depression needs to be lowered. Limitations: This research is based on a mathematical algorithm to approximate a life-long longitudinal study that identifies community cases of depression. Our findings therefore rely on the validity of the statistics used. Extrapolation is limited to populations with an actual suicide rate of 17/100,000 or less and a lifetime prevalence of major depression of 17% or more. (C) 1999 Elsevier Science B.V. All rights reserved.
Keyword Clinical Neurology
Depressive Disorder
Major Depression
Youth Suicide
500 Psychiatric Outpatients
Youth Suicide
Q-Index Code C1
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Faculty of Humanities and Social Sciences - Publications
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Citation counts: TR Web of Science Citation Count  Cited 105 times in Thomson Reuters Web of Science Article | Citations
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Created: Mon, 20 Aug 2007, 01:58:44 EST