Deceased donor renal transplantation - does side matter?

Johnson, David W., Mudge, David W., Kaisar, Mohammed O., Campbell, Scott B., Hawley, Carmel M., Isbel, Nicole M., Wall, Daryl, Griffin, Anthony, Preston, John and Nicol, David L. (2006) Deceased donor renal transplantation - does side matter?. Nephrology Dialysis Transplantation, 21 9: 2583-2588. doi:10.1093/ndt/gfl268


Author Johnson, David W.
Mudge, David W.
Kaisar, Mohammed O.
Campbell, Scott B.
Hawley, Carmel M.
Isbel, Nicole M.
Wall, Daryl
Griffin, Anthony
Preston, John
Nicol, David L.
Title Deceased donor renal transplantation - does side matter?
Journal name Nephrology Dialysis Transplantation   Check publisher's open access policy
ISSN 0931-0509
1460-2385
Publication date 2006-01-01
Year available 2006
Sub-type Article (original research)
DOI 10.1093/ndt/gfl268
Volume 21
Issue 9
Start page 2583
End page 2588
Total pages 6
Editor N. Lameire
Place of publication Oxford, United Kingdom
Publisher Oxford University Press
Language eng
Subject C1
730118 Organs, diseases and abnormal conditions not elsewhere classified
110312 Nephrology and Urology
Formatted abstract
Background. The aim of the present study was to determine whether the deceased donor kidney side (left or right kidney) was predictive of subsequent kidney transplant outcomes.

Methods
. A retrospective analysis was undertaken of the left–right deceased donor kidney pairs transplanted into recipients with end-stage renal failure in Queensland between 1 April 1994 and 31 March 2004.

Results
. A total of 201 left–right deceased donor kidney pairs were transplanted into 402 patients. The baseline characteristics of the recipients in the two groups were comparable, except that the patients receiving right kidneys had lower body mass indices and shorter cold ischaemic times. No differences were seen between the left and right kidney recipient groups with respect to operative duration (3.02 ± 0.67 vs 3.12 ± 0.72 h, P = 0.16), warm ischaemic time (0.62 ± 0.18 vs 0.65 ± 0.21, P = 0.09), delayed graft function (4 vs 6%, respectively, P = 0.26) or a composite vascular, haemorrhagic, ureteric and infective post-operative complication end-point (22 vs 22%, P = 0.90). Estimated glomerular filtration rates were almost identical at 1 month (52.7 ± 39.6 vs 51.0 ± 24.0 ml/min/1.73 m2, P = 0.34) and remained comparable thereafter. Respective death-censored graft survival rates for left and right kidney recipients were 100 and 100% at 1 year, 99.4 and 96.4% at 3 years and 96.3 and 95.5% at 5 years, respectively (P = 0.67).

Conclusions
. Although left and right deceased donor kidneys present different operative challenges, the present results suggest that the probability of early post-operative complications, delayed graft function, impaired early and medium-term renal allograft function or death-censored graft failure is comparable between left and right kidney recipients.
Keyword Transplantation
Urology & Nephrology
Delayed Graft Function
Graft Survival
Kidney Transplantation
Left Kidney
Post-operative Complications
Right Kidney
Live Kidney Donors
Vein Extension
Graft Failure
Nephrectomy
Q-Index Code C1
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
2007 Higher Education Research Data Collection
School of Medicine Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 5 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 8 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Wed, 15 Aug 2007, 20:00:55 EST