Reversible active switching of the mechanical properties of a peptide film at a fluid-fluid interface

Dexter, Annette F., Malcolm, Andrew S. and Middelberg, Anton P. J. (2006) Reversible active switching of the mechanical properties of a peptide film at a fluid-fluid interface. Nature Materials, 5 6: 502-506. doi:10.1038/nmat1653


Author Dexter, Annette F.
Malcolm, Andrew S.
Middelberg, Anton P. J.
Title Reversible active switching of the mechanical properties of a peptide film at a fluid-fluid interface
Journal name Nature Materials   Check publisher's open access policy
ISSN 1476-1122
Publication date 2006-01-01
Year available 2006
Sub-type Article (original research)
DOI 10.1038/nmat1653
Open Access Status Not yet assessed
Volume 5
Issue 6
Start page 502
End page 506
Total pages 5
Editor Vincent Dusastre
Place of publication London
Publisher Nature Publishing Group
Language eng
Subject C1
290699 Chemical Engineering not elsewhere classified
291804 Nanotechnology
299999 Engineering and Technology not elsewhere classified
670499 Other
670799 Other
670199 Processed food products and beverages not elsewhere classified
Abstract Designer peptides have recently been developed as building blocks for novel self-assembled materials with stimuli-responsive properties. To date, such materials have been based on self-assembly in bulk aqueous solution or at solid-fluid interfaces. We have designed a 21-residue peptide, AM1, as a stimuli-responsive surfactant that switches molecular architectures at a fluid-fluid interface in response to changes in bulk aqueous solution composition. In the presence of divalent zinc at neutral pH, the peptide forms a mechanically strong 'film state'. In the absence of metal ions or at acid pH, the peptide adsorbs to form a mobile 'detergent state'. The two interfacial states can be actively and reversibly switched. Switching between the two states by a change in pH or the addition of a chelating agent leads to rapid emulsion coalescence or foam collapse. This work introduces a new class of surfactants that offer an environmentally friendly approach to control the stability of interfaces in foams, emulsions and fluid-fluid interfaces more generally.
Keyword Chemistry, Physical
Q-Index Code C1
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Excellence in Research Australia (ERA) - Collection
School of Chemical Engineering Publications
 
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Created: Wed, 15 Aug 2007, 19:11:44 EST