Executive control of working memory in schizophrenia

Oram, Joanne, Geffen, Gina M., Geffen, Laurie B., Kavanagh, David J. and McGrath, John J. (2005) Executive control of working memory in schizophrenia. Psychiatry Research, 135 2: 81-90. doi:10.1016/j.psychres.2005.03.002

Author Oram, Joanne
Geffen, Gina M.
Geffen, Laurie B.
Kavanagh, David J.
McGrath, John J.
Title Executive control of working memory in schizophrenia
Journal name Psychiatry Research   Check publisher's open access policy
ISSN 0165-1781
Publication date 2005-01-01
Sub-type Article (original research)
DOI 10.1016/j.psychres.2005.03.002
Volume 135
Issue 2
Start page 81
End page 90
Total pages 10
Editor Monte S. Buchsbaum
Place of publication Shannon, Co. Clare Ireland
Publisher Elsevier Ireland
Language eng
Subject 380103 Biological Psychology (Neuropsychology, Psychopharmacology, Physiological Psychology)
730211 Mental health
Abstract There is considerable evidence that working memory impairment is a common feature of schizophrenia. The present study assessed working memory and executive function in 54 participants with schizophrenia, and a group of 54 normal controls matched to the patients on age, gender and estimated premorbid IQ, using traditional and newer measures of executive function and two dual tasks-Telephone Search with Counting and the Memory Span and Tracking Task. Results indicated that participants with schizophrenia were significantly impaired on all standardised measures of executive function with the exception of a composite measure of the Trail Making Test. Results for the dual task measures demonstrated that while the participants with schizophrenia were unimpaired on immediate digit span recall over a 2-min period, they recalled fewer digit strings and performed more poorly on a tracking task (box-crossing task) compared with controls. In addition, participants with schizophrenia performed more poorly on the tracking task when they were required to simultaneously recall digits strings than when they performed this task alone. Contrary to expectation, results of the telephone search task under dual conditions were not significantly different between groups. These results may reflect the insufficient complexity of the tone-counting task as an interference task. Overall, the present study showed that participants with schizophrenia appear to have a restricted impairment of their working memory system that is evident in tasks in which the visuospatial sketchpad slave system requires central executive control. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
Keyword Psychiatry
Working Memory
Central Executive
Executive Function
Adult Reading Test
Phonological Loop
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2006 Higher Education Research Data Collection
School of Psychology Publications
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Citation counts: TR Web of Science Citation Count  Cited 14 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 16 times in Scopus Article | Citations
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Created: Wed, 15 Aug 2007, 17:30:11 EST