Arousal and re-feeding rapidly restores digestive tract morphology following aestivation in green-striped burrowing frogs

Cramp, R. L. and Franklin, C. E. (2005) Arousal and re-feeding rapidly restores digestive tract morphology following aestivation in green-striped burrowing frogs. Comparative Biochemistry And Physiology A-molecular & Integrative Physiology, 142 4: 451-460. doi:10.1016/j.cbpa.2005.09.013


Author Cramp, R. L.
Franklin, C. E.
Title Arousal and re-feeding rapidly restores digestive tract morphology following aestivation in green-striped burrowing frogs
Journal name Comparative Biochemistry And Physiology A-molecular & Integrative Physiology   Check publisher's open access policy
ISSN 1095-6433
Publication date 2005-01-01
Year available 2005
Sub-type Article (original research)
DOI 10.1016/j.cbpa.2005.09.013
Open Access Status
Volume 142
Issue 4
Start page 451
End page 460
Total pages 10
Editor Patrick J Walsh (Editor-in-Chief)
Thomas P Mommsen (Editor -in-Chief)
Place of publication United States
Publisher Elsevier Science Inc
Language eng
Subject C1
270604 Comparative Physiology
780107 Studies in human society
Abstract During aestivation, the gut of the green-striped burrowing frog, Cyclorana alboguttata undergoes significant morphological down-regulation. Despite the potential impact such changes might have on the re-feeding efficiency of these animals following aestivation, they appear to be as efficient at digesting their first meals as active, non-aestivating animals. Such efficiency might come about by the rapid restoration of intestinal morphology with both arousal from aestivation and the initial stages of re-feeding. Consequently, this study sought to determine what morphological changes to the intestine accompany arousal and re-feeding following 3 months of aestivation. Arousal from aestivation alone had a marked impact on many morphological parameters, including small and large intestine masses, small intestinal length, LF heights, enterocyte cross-sectional area and microvilli height and density. In addition, the onset of re-feeding was correlated with an immediate reversal of many morphological parameters affected by 3 months of aestivation. Those parameters that had not returned to control levels within 36 h of feeding generally had returned to control values by the completion of digestion (i.e. defecation of the meal). Re-feeding was also associated with several changes in enterocyte morphology including the incorporation in intracytoplasmic lipid droplets and the return of enterocyte nuclear material to the 'active' euchromatin state: In conclusion, morphological changes to the gut of aestivating frogs which occur during aestivation are transitory and rapidly reversible with both arousal from aestivation and re-feeding. The proximate causes behind these transitions and their functional significance are discussed. (C) 2005 Elsevier Inc. All rights reserved.
Keyword Biochemistry & Molecular Biology
Physiology
Zoology
Up-regulation
Small Intestine
Enterocyte
Prolonged Starvation
Fasting
Food-deprivation
Recovery
Rat Small-intestine
Protein-synthesis
Physiological-responses
Structural Flexibility
Gastrointestinal-tract
Cyclorana-alboguttata
Mucosal Structure
Seasonal-changes
Starvation
Hibernation
Q-Index Code C1
Institutional Status UQ

 
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Created: Wed, 15 Aug 2007, 17:09:25 EST