An experimental and finite element poroelastic creep response analysis of an intervertebral hydrogel disc model in axial compression

Silva, P., Crozier, S., Veidt, M. and Pearcy, M. J. (2005) An experimental and finite element poroelastic creep response analysis of an intervertebral hydrogel disc model in axial compression. Journal of Materials Science-materials In Medicine, 16 7: 663-669. doi:10.1007/s10856-005-2538-0


Author Silva, P.
Crozier, S.
Veidt, M.
Pearcy, M. J.
Title An experimental and finite element poroelastic creep response analysis of an intervertebral hydrogel disc model in axial compression
Journal name Journal of Materials Science-materials In Medicine   Check publisher's open access policy
ISSN 0957-4530
Publication date 2005-07-01
Year available 2005
Sub-type Article (original research)
DOI 10.1007/s10856-005-2538-0
Open Access Status Not yet assessed
Volume 16
Issue 7
Start page 663
End page 669
Total pages 7
Editor William Bonfield
Place of publication Netherlands
Publisher Kluwer Academic
Language eng
Subject C1
290399 Manufacturing Engineering not elsewhere classified
780102 Physical sciences
Abstract A hydrogel intervertebral disc (lVD) model consisting of an inner nucleus core and an outer anulus ring was manufactured from 30 and 35% by weight Poly(vinyl alcohol) hydrogel (PVA-H) concentrations and subjected to axial compression in between saturated porous endplates at 200 N for 11 h, 30 min. Repeat experiments (n = 4) on different samples (N = 2) show good reproducibility of fluid loss and axial deformation. An axisymmetric nonlinear poroelastic finite element model with variable permeability was developed using commercial finite element software to compare axial deformation and predicted fluid loss with experimental data. The FE predictions indicate differential fluid loss similar to that of biological IVDs, with the nucleus losing more water than the anulus, and there is overall good agreement between experimental and finite element predicted fluid loss. The stress distribution pattern indicates important similarities with the biological lVD that includes stress transference from the nucleus to the anulus upon sustained loading and renders it suitable as a model that can be used in future studies to better understand the role of fluid and stress in biological IVDs. (C) 2005 Springer Science + Business Media, Inc.
Keyword Materials Science, Biomaterials
Poly(vinyl Alcohol) Hydrogel
Permeability
Mechanics
Engineering, Biomedical
Q-Index Code C1
Institutional Status UQ
Additional Notes DOI :10.1007/s10856-005-2538-0

 
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Created: Wed, 15 Aug 2007, 16:03:09 EST