Classical cadherin adhesion molecules: coordinating cell adhesion, signaling and the cytoskeleton

Goodwin, M. and Yap, A. S. (2004) Classical cadherin adhesion molecules: coordinating cell adhesion, signaling and the cytoskeleton. Journal of Molecular Histology, 35 8-9: 839-844. doi:10.1007/s10735-004-1833-2


Author Goodwin, M.
Yap, A. S.
Title Classical cadherin adhesion molecules: coordinating cell adhesion, signaling and the cytoskeleton
Journal name Journal of Molecular Histology   Check publisher's open access policy
ISSN 1567-2379
Publication date 2004-01-01
Year available 2004
Sub-type Article (original research)
DOI 10.1007/s10735-004-1833-2
Open Access Status Not yet assessed
Volume 35
Issue 8-9
Start page 839
End page 844
Total pages 6
Place of publication Dordrecht, The Netherlands
Publisher Kluwer Academic Publishers
Language eng
Subject C1
270105 Cellular Interactions (incl. Adhesion, Matrix, Cell Wall)
780105 Biological sciences
Abstract Classical cadherin adhesion molecules are fundamental determinants of tissue organization in both health and disease. Recent advances in understanding the molecular and cellular basis of cadherin function have revealed that these adhesion molecules serve as molecular couplers, linking cell surface adhesion and recognition to both the actin cytoskeleton and cell signalling pathways. We will review some of these developments. to provide an overview of progress in this rapidly-developing area of cell and developmental biology.
Keyword Cell Biology
Plasma-membrane
C-cadherin
Tyrosine Phosphorylation
Contact Formation
Actin-filaments
Alpha-catenin
Beta-catenin
N-cadherin
F-actin
Complex
Q-Index Code C1
Institutional Status UQ

 
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Created: Wed, 15 Aug 2007, 14:50:57 EST