Fourier-domain optical coherence tomography: optimization of signal-to-noise ratio in full space

Zvyagin, A. V. (2004) Fourier-domain optical coherence tomography: optimization of signal-to-noise ratio in full space. Optics Communications, 242 1-3: 97-108. doi:10.1016/j.optcom.2004.07.060


Author Zvyagin, A. V.
Title Fourier-domain optical coherence tomography: optimization of signal-to-noise ratio in full space
Journal name Optics Communications   Check publisher's open access policy
ISSN 0030-4018
Publication date 2004-01-01
Sub-type Article (original research)
DOI 10.1016/j.optcom.2004.07.060
Volume 242
Issue 1-3
Start page 97
End page 108
Total pages 12
Editor F Abels
S Kawata
Place of publication Netherlands
Publisher Elsevier BV North-Holland
Language eng
Subject C1
249901 Biophysics
780102 Physical sciences
249903 Instruments and Techniques
730108 Cancer and related disorders
Abstract Optical coherence tomography (OCT) is an emerging coherence-domain technique capable of in vivo imaging of sub-surface structures at millimeter-scale depth. Its steady progress over the last decade has been galvanized by a breakthrough detection concept, termed spectral-domain OCT, which has resulted in a dramatic improvement of the OCT signal-to-noise ratio of 150 times demonstrated for weakly scattering objects at video-frame-rates. As we have realized, however, an important OCT sub-system remains sub-optimal: the sample arm traditionally operates serially, i.e. in flying-spot mode. To realize the full-field image acquisition, a Fourier holography system illuminated with a swept-source is employed instead of a Michelson interferometer commonly used in OCT. The proposed technique, termed Fourier-domain OCT, offers a new leap in signal-to-noise ratio improvement, as compared to flying-spot OCT systems, and represents the main thrust of this paper. Fourier-domain OCT is described, and its basic theoretical aspects, including the reconstruction algorithm, are discussed. (C) 2004 Elsevier B.V. All rights reserved.
Keyword Optics
Optical Coherence Tomography
Fourier Holography
Coherence-domain Imaging
Signal-to-noise Ratio
Retinal Blood-flow
Interferometry
Holography
Q-Index Code C1

Document type: Journal Article
Sub-type: Article (original research)
Collections: 2005 Higher Education Research Data Collection
School of Physical Sciences Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 11 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 16 times in Scopus Article | Citations
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Created: Wed, 15 Aug 2007, 14:34:47 EST