Skin Penetration

Machado, A. C. H. R., Lopes, P. S., Raffier, C. P., Haridass, I. N., Roberts, M., Grice, J. and Leite-Silva, V. R. (2017). Skin Penetration. In Cosmetic Science and Technology: Theoretical Principles and Applications (pp. 741-755) Amsterdam, Netherlands: Elsevier . doi:10.1016/B978-0-12-802005-0.00046-X


Author Machado, A. C. H. R.
Lopes, P. S.
Raffier, C. P.
Haridass, I. N.
Roberts, M.
Grice, J.
Leite-Silva, V. R.
Title of chapter Skin Penetration
Title of book Cosmetic Science and Technology: Theoretical Principles and Applications
Place of Publication Amsterdam, Netherlands
Publisher Elsevier
Publication Year 2017
Sub-type Research book chapter (original research)
DOI 10.1016/B978-0-12-802005-0.00046-X
Open Access Status Not yet assessed
ISBN 9780128020548
9780128020050
Chapter number 46
Start page 741
End page 755
Total pages 15
Total chapters 51
Language eng
Subjects 1600 Chemistry
Abstract/Summary The cosmetic industry continues to expand worldwide. The claims described on a cosmetic product label or in promotional material must be substantiated with scientific data or clinical studies, ensuring that the product actually has the promised effect. Cosmetics must be safe to use over a long term, so safety assurance is critical. Testing the skin penetration of cosmetic actives and excipients is one example of the safety measures that are required. With the prohibition of animal testing for cosmetic evaluation in Europe, product safety has had to be assessed by in vitro methods or in vivo human studies. This has led to a new set of challenges to find and validate in vitro techniques that reliably predict in vivo human responses.
Keyword Cosmetic
Skin barrier
Skin imaging
Skin penetration
Stratum corneum
Tape stripping
Topical application
Q-Index Code B1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Book Chapter
Collections: HERDC Pre-Audit
Faculty of Medicine
 
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Created: Fri, 20 Apr 2018, 11:04:05 EST