Building towards a standardised approach to biocorrosion studies: a review of factors influencing Mg corrosion in vitro pertinent to in vivo corrosion 建立一个生物腐蚀研究的标准化方法:与体内腐蚀相关的体外镁腐蚀影响因素综述

Johnston, Sean, Dargusch, Matthew and Atrens, Andrej (2017) Building towards a standardised approach to biocorrosion studies: a review of factors influencing Mg corrosion in vitro pertinent to in vivo corrosion 建立一个生物腐蚀研究的标准化方法:与体内腐蚀相关的体外镁腐蚀影响因素综述. Science China Materials, 61 4: 475-500. doi:10.1007/s40843-017-9173-7


Author Johnston, Sean
Dargusch, Matthew
Atrens, Andrej
Title Building towards a standardised approach to biocorrosion studies: a review of factors influencing Mg corrosion in vitro pertinent to in vivo corrosion 建立一个生物腐蚀研究的标准化方法:与体内腐蚀相关的体外镁腐蚀影响因素综述
Journal name Science China Materials   Check publisher's open access policy
ISSN 2199-4501
2095-8226
Publication date 2017-12-27
Sub-type Article (original research)
DOI 10.1007/s40843-017-9173-7
Open Access Status Not yet assessed
Volume 61
Issue 4
Start page 475
End page 500
Total pages 16
Place of publication Beijing, China
Publisher Science China Press
Language eng
Subject 2500 Materials Science
Abstract The factors that influence magnesium (Mg) corrosion in vitro are systematically evaluated from a review of the relevant literature. We analysed the influence of the following factors on Mg biocorrosion in vitro: (i) inorganic ions, including both anions and cations, (ii) organic components such as proteins, amino acids and vitamins, and (iii) experimental parameters such as temperature, pH, buffer system and flow rate. Considerations and recommendations towards a standardised approach to in vitro biocorrosion testing are given. Several potential simulated body fluids are recommended. Implementing a standardised approach to experimental parameters has the potential to significantly reduce variability between in vitro biocorrosion tests, and to help build towards a methodology that accurately and consistently mimics in vivo corrosion. However, there are also knowledge gaps with regard to how best to characterise the in vivo environment and corrosion mechanism. The assumption that blood plasma is the correct bodily fluid upon which to base in vitro methodologies is examined, and factors that influence the corrosion mechanism in vivo, such as specimen encapsulation, bear consideration for further studies.
Keyword biocorrosion
biodegradable metals
corrosion
in vitro
in vivo
magnesium
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Mechanical & Mining Engineering Publications
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School of Engineering Publications
 
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Created: Fri, 20 Apr 2018, 04:44:51 EST