Dehydroepiandosterone and its sulphate enhance memory retention in day-old chicks

Migues, PV, Johnston, ANB and Rose, SPR (2002) Dehydroepiandosterone and its sulphate enhance memory retention in day-old chicks. Neuroscience, 109 2: 243-251. doi:10.1016/S0306-4522(01)00471-7


Author Migues, PV
Johnston, ANB
Rose, SPR
Title Dehydroepiandosterone and its sulphate enhance memory retention in day-old chicks
Journal name Neuroscience   Check publisher's open access policy
ISSN 0306-4522
Publication date 2002-01-01
Year available 2002
Sub-type Article (original research)
DOI 10.1016/S0306-4522(01)00471-7
Volume 109
Issue 2
Start page 243
End page 251
Total pages 9
Place of publication OXFORD
Publisher PERGAMON-ELSEVIER SCIENCE LTD
Language eng
Abstract We report the presence of dehydroepiandosterone (DHEA) and DHEA sulphate (DHEA-S) in the day-old-chick brain, and their possible role in memory formation. DHEA and DHEA-S were present in the brain at higher concentrations than in the plasma, Radioimmunoassay examination of the intermediate medial hyperstriatum ventrale 5 or 30 min after training or the lobus parolfactorius 60 or 120 min after training on the passive avoidance task did not show learning-related differences in absolute levels of DHEA or DHEA-S. However, bilateral intracerebral injections of DHEA or DHEA-S before or after training on the weak passive avoidance task enhanced recall 24 h after training. Memory retention was enhanced by administration of DHEA and DHEA-S 15 min before training or 30 and 60 but not 180 min after training.
Keyword Avian
DHEA
DHEA-S
Neurosteroids
Passive avoidance learning
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collections: ResearcherID Downloads
Scopus Import
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 30 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 34 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Fri, 06 Apr 2018, 01:00:37 EST by Web Cron on behalf of Learning and Research Services (UQ Library)