Indolent systemic mastocytosis: A case and review of the current available treatment options

Lee, Yvonne, Wood, Peter and Soyer, H. Peter (2013) Indolent systemic mastocytosis: A case and review of the current available treatment options. Dermatology Online Journal, 19 6: 1-6.

Author Lee, Yvonne
Wood, Peter
Soyer, H. Peter
Title Indolent systemic mastocytosis: A case and review of the current available treatment options
Journal name Dermatology Online Journal   Check publisher's open access policy
ISSN 1087-2108
Publication date 2013-06-28
Sub-type Article (original research)
Open Access Status Not yet assessed
Volume 19
Issue 6
Start page 1
End page 6
Total pages 6
Place of publication Oakland, CA United States
Publisher University of California
Language eng
Subject 2708 Dermatology
Abstract Mastocytosis denotes a heterogeneous group of disorders characterized by abnormal growth and accumulation of mast cells. Cutaneous mastocytosis is characterized by skin-limited disease and is the most common subtype. Systemic mastocytosis has extracutaneous organ involvement with variable symptomatology and prognosis. Clinical manifestations are secondary to mediator release or direct organ infiltration of mast cells. Current available treatment for systemic mastocytosis is non-curative with conventional symptom-directed therapy for all subtypes. Cytoreductive agents are available for those with refractory symptoms or extensive extracutaneous disease. To date, clinical responses remain mixed and systemic mastocytosis is still an incurable condition.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Fri, 30 Mar 2018, 01:13:54 EST