Indocyanine green-incorporating nanoparticles for cancer theranostics

Wang, Haolu, Li, Xinxing, Tse, Brian Wan-Chi, Yang, Haotian, Thorling, Camilla A., Liu, Yuxin, Touraud, Margaux, Chouane, Jean Batiste, Liu, Xin, Roberts, Michael S. and Liang, Xiaowen (2018) Indocyanine green-incorporating nanoparticles for cancer theranostics. Theranostics, 8 5: 1227-1242. doi:10.7150/thno.22872

Author Wang, Haolu
Li, Xinxing
Tse, Brian Wan-Chi
Yang, Haotian
Thorling, Camilla A.
Liu, Yuxin
Touraud, Margaux
Chouane, Jean Batiste
Liu, Xin
Roberts, Michael S.
Liang, Xiaowen
Title Indocyanine green-incorporating nanoparticles for cancer theranostics
Journal name Theranostics   Check publisher's open access policy
ISSN 1838-7640
Publication date 2018-01-01
Year available 2018
Sub-type Critical review of research, literature review, critical commentary
DOI 10.7150/thno.22872
Open Access Status Not yet assessed
Volume 8
Issue 5
Start page 1227
End page 1242
Total pages 16
Place of publication Sydney, NSW Australia
Publisher Ivyspring International Publisher
Language eng
Subject 2701 Medicine (miscellaneous)
3001 Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
Abstract Indocyanine green (ICG) is a near-infrared dye that has been used in the clinic for retinal angiography, and defining cardiovascular and liver function for over 50 years. Recently, there has been an increasing interest in the incorporation of ICG into nanoparticles (NPs) for cancer theranostic applications. Various types of ICG-incorporated NPs have been developed and strategically functionalised to embrace multiple imaging and therapeutic techniques for cancer diagnosis and treatment. This review systematically summaries the biodistribution of various types of ICG-incorporated NPs for the first time, and discusses the principles, opportunities, limitations, and application of ICG-incorporated NPs for cancer theranostics. We believe that ICG-incorporated NPs would be a promising multifunctional theranostic platform in oncology and facilitate significant advancements in this research-active area.
Keyword Near-Infrared Fluorescence
Mesoporous Silica Nanoparticles
Photoacoustic Contrast Agent
Lipid-Polymer Nanoparticles
Tumor Targeting Efficiency
Sentinel Lymph-Node
Photothermal Therapy
Photodynamic Therapy
Q-Index Code C1
Q-Index Status Provisional Code
Grant ID APP1125794
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: HERDC Pre-Audit
School of Biomedical Sciences Publications
UQ Diamantina Institute Publications
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Created: Sat, 24 Feb 2018, 20:10:44 EST