Notching a new pathway in vascular flow sensing

Lagendijk, Anne K., Yap, Alpha S. and Hogan, Benjamin M. (2018) Notching a new pathway in vascular flow sensing. Trends in Cell Biology, 28 3: 173-175. doi:10.1016/j.tcb.2017.12.003


Author Lagendijk, Anne K.
Yap, Alpha S.
Hogan, Benjamin M.
Title Notching a new pathway in vascular flow sensing
Journal name Trends in Cell Biology   Check publisher's open access policy
ISSN 1879-3088
0962-8924
Publication date 2018-01-02
Year available 2018
Sub-type Article (original research)
DOI 10.1016/j.tcb.2017.12.003
Open Access Status Not yet assessed
Volume 28
Issue 3
Start page 173
End page 175
Total pages 3
Place of publication Kidlington, Oxford, United Kingdom
Publisher Elsevier
Language eng
Abstract Vascular barrier function is controlled at cell-cell junctions in response to blood flow, but how vascular endothelial cells sense and respond to flow remains to be understood. A recent study describes a flow-sensing pathway involving non-canonical Notch and cadherin signaling that sheds new light on mechanisms controlling the endothelial barrier.
Keyword Notch
VE-cadherin
Endothelial
Endothelial barrier
Vascular
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
Institute for Molecular Bioscience - Publications
 
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Created: Wed, 10 Jan 2018, 12:08:19 EST