Primary adrenal lymphoma with initial presentation concerning for bilateral adrenal pheochromocytomas

Joseph, Flavian Grace, Cook, Sheila and Gowda, Durgesh (2017) Primary adrenal lymphoma with initial presentation concerning for bilateral adrenal pheochromocytomas. BMJ Case Reports, 2017 . doi:10.1136/bcr-2017-220549


Author Joseph, Flavian Grace
Cook, Sheila
Gowda, Durgesh
Title Primary adrenal lymphoma with initial presentation concerning for bilateral adrenal pheochromocytomas
Journal name BMJ Case Reports   Check publisher's open access policy
ISSN 1757-790X
Publication date 2017-08-22
Year available 2017
Sub-type Article (original research)
DOI 10.1136/bcr-2017-220549
Open Access Status Not yet assessed
Volume 2017
Place of publication London, United Kingdom
Publisher BMJ Publishing Group
Language eng
Abstract Primary adrenal non-Hodgkin’s lymphoma is rarely encountered. Clinical presentation is non-specific with fatigue, abdominal pain and B-symptoms being more commonly reported. We report a case of primary bilateral adrenal lymphoma who initially presented with clinical features suspicious for pheochromocytoma. The patient was recently diagnosed with hypertension and had a family history of early ischaemic heart disease. Plasma free metanephrines were also elevated. Pheochromocytoma was deemed unlikely following multiple investigations and the diagnosis of lymphoma was made following adrenal biopsy. Partial response was noted on positron emission tomography CT scan following four cycles of chemotherapy but failed to remit after six cycles of chemotherapy. Subsequently, he received 20 fractions of radiation to his adrenal glands and is now awaiting further imaging. The presentation of primary adrenal lymphoma can be variable and given that the diagnosis is obtained through tissue sampling, pheochromocytoma should be excluded due to risk of a potentially fatal adrenergic crisis.
Keyword Adrenal disorders
Endocrine system
Haematology (incl blood transfusion)
Medical education
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
Faculty of Medicine
Rural Clinical School Publications
 
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Created: Tue, 09 Jan 2018, 13:25:07 EST by Jacky Cribb on behalf of Learning and Research Services (UQ Library)