Cyclotriphosphazene, a scaffold for 19 F MRI contrast agents

Emel Önal, Cheng Zhang, Derya Davarcı, Ümit İşci, Guillaume Pilet, Andrew Whittaker and Fabienne Dumoulin (2017) Cyclotriphosphazene, a scaffold for 19 F MRI contrast agents. Tetrahedron Letters, 59 6: 521-523. doi:10.1016/j.tetlet.2017.12.032

Author Emel Önal
Cheng Zhang
Derya Davarcı
Ümit İşci
Guillaume Pilet
Andrew Whittaker
Fabienne Dumoulin
Title Cyclotriphosphazene, a scaffold for 19 F MRI contrast agents
Journal name Tetrahedron Letters   Check publisher's open access policy
ISSN 1873-3581
Publication date 2017-12-09
Year available 2017
Sub-type Article (original research)
DOI 10.1016/j.tetlet.2017.12.032
Open Access Status Not yet assessed
Volume 59
Issue 6
Start page 521
End page 523
Total pages 3
Place of publication OXFORD
Publisher Elsevier Ltd
Language eng
Subject 1303 Biochemistry
3002 Drug Discovery
1605 Organic Chemistry
Abstract A cyclotriphosphazene substituted with six 3,5-bis(trifluoromethyl) benzyloxy units was designed as a novel F MRI contrast agent. The resulting molecule has 36 magnetically equivalent fluorine atoms and exhibited suitable MRI properties with high imaging sensitivity, confirming the proof-of-concept as a convenient scaffold for the production of new F MRI contrasts agents.
Keyword F MRI
Contrast agent
Q-Index Code C1
Q-Index Status Provisional Code
Grant ID CE140100036
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
Australian Institute for Bioengineering and Nanotechnology Publications
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Created: Thu, 04 Jan 2018, 08:55:05 EST by Cheng Zhang on behalf of Aust Institute for Bioengineering & Nanotechnology