Antibiotic pharmacokinetic/pharmacodynamic considerations in the critically ill

Udy, Andrew A., Roberts, Jason A. and Lipman, Jeffrey Antibiotic pharmacokinetic/pharmacodynamic considerations in the critically ill. Gateway East, Singapore: Springer Singapore, 2017. doi:10.1007/978-981-10-5336-8


Author Udy, Andrew A.
Roberts, Jason A.
Lipman, Jeffrey
Title Antibiotic pharmacokinetic/pharmacodynamic considerations in the critically ill
Place of Publication Gateway East, Singapore
Publisher Springer Singapore
Publication year 2017
Sub-type Research book (original research)
DOI 10.1007/978-981-10-5336-8
Open Access Status Not yet assessed
ISBN 9789811053368
9789811053351
Language eng
Start page 1
End page 275
Total number of pages 275
Year available 2018
Subjects 2700 Medicine
3000 Pharmacology, Toxicology and Pharmaceutics
Abstract/Summary This book provides unique insights into the issues that drive modified dosing regimens for antibiotics in the critically ill. Leading international authors provide their commentary alongside a summary of existing evidence on how to effectively dose antibiotics. Severe infection frequently necessitates admission to the intensive care unit (ICU). Equally, nosocomial sepsis often complicates the clinical course in ICU. Early, appropriate application of antibiotic therapy remains a cornerstone of effective management. However, this is challenging in the critical care environment, given the significant changes in patient physiology and organ function frequently encountered. Being cognisant of these factors, prescribers need to consider modified dosing regimens, not only to ensure adequate drug exposure, and therefore the greatest chance of clinical cure, but also to avoid encouraging drug resistance.
Q-Index Code A1
Q-Index Status Provisional Code
Institutional Status UQ

 
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Created: Sat, 16 Dec 2017, 21:03:59 EST