Mammalian target of rapamycin inhibitors and clinical outcomes in adult kidney transplant recipients

Badve, Sunil V., Pascoe, Elaine M., Burke, Michael, Clayton, Philip A., Campbell, Scott B., Hawley, Carmel M., Lim, Wai H., McDonald, Stephen P., Wong, Germaine and Johnson, David W. (2016) Mammalian target of rapamycin inhibitors and clinical outcomes in adult kidney transplant recipients. Clinical Journal of the American Society of Nephrology, 11 10: 1845-1855. doi:10.2215/CJN.00190116


Author Badve, Sunil V.
Pascoe, Elaine M.
Burke, Michael
Clayton, Philip A.
Campbell, Scott B.
Hawley, Carmel M.
Lim, Wai H.
McDonald, Stephen P.
Wong, Germaine
Johnson, David W.
Title Mammalian target of rapamycin inhibitors and clinical outcomes in adult kidney transplant recipients
Journal name Clinical Journal of the American Society of Nephrology   Check publisher's open access policy
ISSN 1555-905X
1555-9041
Publication date 2016-10-07
Year available 2016
Sub-type Article (original research)
DOI 10.2215/CJN.00190116
Open Access Status Not yet assessed
Volume 11
Issue 10
Start page 1845
End page 1855
Total pages 11
Place of publication Washington, DC, United States
Publisher American Society of Nephrology
Language eng
Abstract Background and objectives Emerging evidence from recently published observational studies and an individual patient data meta-analysis shows that mammalian target of rapamycin inhibitor use in kidney transplantation is associated with increased mortality. Therefore, all-cause mortality and allograft loss were compared between use and nonuse of mammalian target of rapamycin inhibitors in patients from Australia and New Zealand, where mammalian target of rapamycin inhibitor use has been greater because of heightened skin cancer risk.
Keyword Allografts
Cohort studies
Graft survival
Humans
Immunosuppression
Kidney transplantation
Longitudinal studies
Mortality
Risk factors
Skin neoplasms
Transplant recipients
Transplantation, homologous
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Medicine Publications
 
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Created: Sat, 16 Dec 2017, 15:29:41 EST