Changes in serum carotenoids in subjects with colorectal adenomas after 24 mo of β-carotene supplementation

Wahlqvist, Mark L., Wattanapenpaiboon, Naiyana, Macrae, Finlay A., Lambert, John R., MacLennan, Robert, Hsu-Hag, Bridget H.-H., Gratten, Helen, Battistutta, Diana, Russell, Anne, Norrie, Mark, Knight, Ngaire, Walker, Maya, Ravens, Jenny, Noad, Helen, Askew, Allan, Cowen, Alistaire, Pollard, Errol, Roberts, Roderick, Robinson, Bill, Stitz, Russell, Walker, Donald, Ward, Michael, Buttenshaw, Ronald, Ford, Cathy, Gaffney, Philip, Lovell, Geoffrey, Kerswill, Warren, Thomas, Mansel, Bain, Christopher, Barnes, Philip, Barr, Gavin, Bokey, Les, Chapuis, Pierre, Cowlishaw, James, Goulston, Kerry, Hughes, Walter, Jones, Brian, Killingback, Mark, McDonald, Charles, Ngu, Meng, Read, Robert, Newland, Ronald, Abraham, Jane, Lloyd, Coral, Paustie, Stephanie, Campbell, Jenny, Hangar, Gabrielle, Macrae, Finlay, Penfold, J. Campbell, St John, D. James, Brouwer, Ruby, Blackley, Marina, Gibson, Kay, Selbie, Lisa, Eaves, Robert, Korman, Mel, McIntyre, Richard, McLeish, John, Balazs, Nicholas, Lambert, John, Wahlqvist, Mark, Elliott, Ross, Brown, James and Topping, David (1994) Changes in serum carotenoids in subjects with colorectal adenomas after 24 mo of β-carotene supplementation. American Journal of Clinical Nutrition, 60 6: 936-943.

Author Wahlqvist, Mark L.
Wattanapenpaiboon, Naiyana
Macrae, Finlay A.
Lambert, John R.
MacLennan, Robert
Hsu-Hag, Bridget H.-H.
Gratten, Helen
Battistutta, Diana
Russell, Anne
Norrie, Mark
Knight, Ngaire
Walker, Maya
Ravens, Jenny
Noad, Helen
Askew, Allan
Cowen, Alistaire
Pollard, Errol
Roberts, Roderick
Robinson, Bill
Stitz, Russell
Walker, Donald
Ward, Michael
Buttenshaw, Ronald
Ford, Cathy
Gaffney, Philip
Lovell, Geoffrey
Kerswill, Warren
Thomas, Mansel
Bain, Christopher
Barnes, Philip
Barr, Gavin
Bokey, Les
Chapuis, Pierre
Cowlishaw, James
Goulston, Kerry
Hughes, Walter
Jones, Brian
Killingback, Mark
McDonald, Charles
Ngu, Meng
Read, Robert
Newland, Ronald
Abraham, Jane
Lloyd, Coral
Paustie, Stephanie
Campbell, Jenny
Hangar, Gabrielle
Macrae, Finlay
Penfold, J. Campbell
St John, D. James
Brouwer, Ruby
Blackley, Marina
Gibson, Kay
Selbie, Lisa
Eaves, Robert
Korman, Mel
McIntyre, Richard
McLeish, John
Balazs, Nicholas
Lambert, John
Wahlqvist, Mark
Elliott, Ross
Brown, James
Topping, David
Title Changes in serum carotenoids in subjects with colorectal adenomas after 24 mo of β-carotene supplementation
Journal name American Journal of Clinical Nutrition   Check publisher's open access policy
ISSN 0002-9165
Publication date 1994-12-01
Sub-type Article (original research)
Open Access Status Not yet assessed
Volume 60
Issue 6
Start page 936
End page 943
Total pages 8
Language eng
Subject 2701 Medicine (miscellaneous)
2916 Nutrition and Dietetics
Abstract The effect of β-carotene supplementation on major serum carotenoid fractions (lutein/zeaxanthin, β-cryptoxanthin, lycopene, α-carotene, and β-carotene) was investigated in 224 people with colorectal adenomas (139 men, 85 women) recruited for the Australian Polyp Prevention Project (APPP). Each subject was randomly assigned to take either 20 mg β-carotene/d or placebo over 24 mo. Besides the expected increase in serum concentration of β-carotene (1073% in men, 839% in women), lycopene (176% in men) and α- carotene (211% in men and 166% in women) concentrations were also increased after body mass index, baseline concentration, change in respective carotenoid intake, and other confounding factors were adjusted for. The increase in serum concentrations of these carotenoids after β-carotene supplementation suggests that β-carotene may interact biologically with other carotenoids and such interaction would need to be taken into consideration when the protective effect of β-carotene supplementation for cancer or other diseases is examined.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
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Created: Fri, 15 Dec 2017, 05:38:45 EST