Cardiometabolic disease leading to heart failure: better fat and fit than lean and lazy

Pandey, Ambarish, Berry, Jarett D. and Lavie, Carl J. (2015) Cardiometabolic disease leading to heart failure: better fat and fit than lean and lazy. Current Heart Failure Reports, 12 5: 302-308. doi:10.1007/s11897-015-0265-5


Author Pandey, Ambarish
Berry, Jarett D.
Lavie, Carl J.
Title Cardiometabolic disease leading to heart failure: better fat and fit than lean and lazy
Journal name Current Heart Failure Reports   Check publisher's open access policy
ISSN 1546-9549
1546-9530
Publication date 2015-10-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1007/s11897-015-0265-5
Open Access Status Not yet assessed
Volume 12
Issue 5
Start page 302
End page 308
Total pages 7
Place of publication Philadelphia, PA, United States
Publisher Springer Healthcare
Language eng
Abstract High body mass index (BMI) and low cardiorespiratory fitness (CRF) are important modifiable risk factors for heart failure (HF). While the individual contributions of CRF and BMI toward risk for HF are well established, the interrelationship between BMI and CRF in modifying long-term HF risk is more complex and not well understood. In this review, we discuss and summarize the available evidence-base on individual and joint contributions of obesity and low CRF toward HF risk, including the potential mechanisms through which these lifestyle risk factors may lead to HF. We also discuss the role of interventions aimed at intentional loss of weight or CRF improvement as potential HF preventive strategies. Finally, the article also highlights the modifying effects of CRF on survival in relation to the obesity paradox in patients with established HF.
Keyword Cardiorespiratory fitness
Exercise
Heart failure
Obesity
Physical activity
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Medicine Publications
 
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Created: Wed, 15 Nov 2017, 13:14:07 EST