Protective isolation precautions for the prevention of nosocomial colonisation and infection in burn patients: A systematic review and meta-analysis.

Raes, Katrien, Blot, Koen, Vogelaers, Dirk, Labeau, Sonia and Blot, Stijn (2017) Protective isolation precautions for the prevention of nosocomial colonisation and infection in burn patients: A systematic review and meta-analysis.. Intensive & critical care nursing, 42 22-29. doi:10.1016/j.iccn.2017.03.005


Author Raes, Katrien
Blot, Koen
Vogelaers, Dirk
Labeau, Sonia
Blot, Stijn
Title Protective isolation precautions for the prevention of nosocomial colonisation and infection in burn patients: A systematic review and meta-analysis.
Journal name Intensive & critical care nursing   Check publisher's open access policy
ISSN 1532-4036
Publication date 2017-10-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.iccn.2017.03.005
Open Access Status Not yet assessed
Volume 42
Start page 22
End page 29
Total pages 8
Abstract To assess the impact of protective isolation precautions on nosocomial colonisation and infection rates in burn patients.

A systematic review and meta-analysis were performed of studies identified through Pubmed and Web of Science. Only articles in English were considered. The Downs and Black tool was used to evaluate their methodological quality. Random-effects meta-analysis obtained pooled risk ratios (RRs) and 95% confidence intervals (CIs) of nosocomial colonisation and infection rates.

Five eligible before-after studies were identified, encompassing a total of 3033 patients (1192 in the experimental group; 1841 in the control group). Varying protective isolation precautions were investigated, resulting in high clinical heterogeneity. Quality assessment revealed overall poor methodological quality. Protective isolation significantly reduces combined colonisation and infection rates compared to baseline care (RR 0.52, 95% CI 0.40-0.69; P<0.0001). Subgroup analyses indicated significant reductions in both nosocomial colonisation (RR 0.65, 95% CI 0.51-0.83; P=0.02) and infection rates (RR 0.53, 95% CI 0.49-0.58; P<0.0001).

Protective isolation precautions appear to decrease the risk of colonization and infection in burn patients. Because of the absence of higher quality study designs, clinical heterogeneity and the small number of studies involved, these results must be interpreted cautiously.
Keyword Burn patient
Colonisation
Infection
Meta-analysis
Nosocomial
Prevention
Protective isolation precautions
Systematic review
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: Pubmed Import
 
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Created: Wed, 15 Nov 2017, 12:39:44 EST