The effect of hydrophilic titanium surface modification on macrophage inflammatory cytokine gene expression

Hamlet, Stephen, Alfarsi, Mohammed, George, Roy and Ivanovski, Saso (2012) The effect of hydrophilic titanium surface modification on macrophage inflammatory cytokine gene expression. Clinical Oral Implants Research, 23 5: 584-590. doi:10.1111/j.1600-0501.2011.02325.x


Author Hamlet, Stephen
Alfarsi, Mohammed
George, Roy
Ivanovski, Saso
Title The effect of hydrophilic titanium surface modification on macrophage inflammatory cytokine gene expression
Journal name Clinical Oral Implants Research   Check publisher's open access policy
ISSN 1600-0501
0905-7161
Publication date 2012-05-01
Year available 2012
Sub-type Article (original research)
DOI 10.1111/j.1600-0501.2011.02325.x
Open Access Status Not yet assessed
Volume 23
Issue 5
Start page 584
End page 590
Total pages 7
Place of publication Hoboken, NJ, United States
Publisher Wiley-Blackwell Publishing
Language eng
Abstract Objectives: Chemical modification of microrough titanium dental implants to produce a hydrophilic surface with increased wettability and improved surface energy has been demonstrated clinically to achieve superior bone wound healing and osseointegration compared to that achieved with a microrough titanium surface alone. As the recruitment of the necessary osseoinductive precursors involved in bone wound healing and osseointegration to the wound site is facilitated by the action of cytokines, this study sought to determine the in vitro effect of hydrophilic surface modification on the expression of pro-inflammatory cytokines from adherent macrophages.
Keyword Cytokine
Gene expression
Hydrophilic
Inflammation
Macrophage
Titanium
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Dentistry Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 38 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 45 times in Scopus Article | Citations
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