Remission in psoriatic arthritis - where are we now?

Coates, Laura C., Conaghan, Philip G., D'Agostino, Maria Antonietta, De Wit, Maarten, FitzGerald, Oliver, Kvien, Tore K., Lories, Rik, Mease, Philip, Nash, Peter, Schett, Georg, Soriano, Enrique R. and Emery, Paul (2017) Remission in psoriatic arthritis - where are we now?. Rheumatology, . doi:10.1093/rheumatology/kex344


Author Coates, Laura C.
Conaghan, Philip G.
D'Agostino, Maria Antonietta
De Wit, Maarten
FitzGerald, Oliver
Kvien, Tore K.
Lories, Rik
Mease, Philip
Nash, Peter
Schett, Georg
Soriano, Enrique R.
Emery, Paul
Title Remission in psoriatic arthritis - where are we now?
Journal name Rheumatology   Check publisher's open access policy
ISSN 1462-0332
1462-0324
Publication date 2017-10-16
Sub-type Article (original research)
DOI 10.1093/rheumatology/kex344
Open Access Status Not yet assessed
Total pages 11
Place of publication Oxford, United Kingdom
Publisher Oxford University Press
Language eng
Abstract Advances in treatments and treatment strategies for PsA have led to many patients responding well to management of their disease, and targeting remission as a treatment goal is now a possibility. Treat to target is a strategy aimed at maximizing benefit, irrespective of the type of medication used, by monitoring disease activity and using it to guide therapy. The measurement of response to treatment has been the subject of wide discussions among experts for some time, and many instruments exist. Comparisons of the different measures and their different strengths and weaknesses is ongoing. The impact of modern imaging techniques on monitoring disease progression is also evolving, and advanced techniques using both MRI and US have the potential to improve management of PsA through identification of risk factors for poor prognosis as well as accurate assessment of inflammation and damage, including subclinical disease. Increased understanding of the pathways that drive the pathogenesis of PsA will be key to identifying specific biomarkers for the disease and developing effective treatment strategies. Targets for response, considerations for use of a treat to target strategy in PsA, different imaging techniques and serological aspects of remission are all discussed in this review, and areas for further research are identified.
Keyword Doppler ultrasound
MRI
PsA
Biomarkers
Disease activity
Imaging
Remission
Tight control
Treat to target
Q-Index Code C1
Q-Index Status Provisional Code
Grant ID 18475
RC-PG-0407-10054
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Medicine Publications
 
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Created: Wed, 25 Oct 2017, 21:01:26 EST