Genomic innovations, transcriptional plasticity and gene loss underlying the evolution and divergence of two highly polyphagous and invasive Helicoverpa pest species

Pearce, S. L., Clarke, D. F., East, P. D., Elfekih, S., Gordon, K. H. J., Jermiin, L. S., McGaughran, A., Oakeshott, J. G., Papanikolaou, A., Perera, O. P., Rane, R. V., Richards, S., Tay, W. T., Walsh, T. K., Anderson, A., Anderson, C. J., Asgari, S., Board, P. G., Bretschneider, A., Campbell, P. M., Chertemps, T., Christeller, J. T., Coppin, C. W., Downes, S. J., Duan, G., Farnsworth, C. A., Good, R. T., Han, L. B., Han, Y. C., Hatje, K., Horne, I., Huang, Y. P., Hughes, D. S. T., Jacquin-Joly, E., James, W., Jhangiani, S., Kollmar, M., Kuwar, S. S., Li, S., Liu, N.-Y., Maibeche, M. T., Miller, J. R., Montagne, N., Perry, T., Qu, J., Songs, S. V., Sutton, G. G., Vogel, H., Walenz, B. P., Xu, W., Zhang, H.-J., Zou, Z., Batterham, P., Edwards, O. R., Feyereisen, R., Gibbs, R. A., Heckel, D. G., McGrath, A., Robin, C., Scherer, S. E., Worley, K. C. and We, Y. D. (2017) Genomic innovations, transcriptional plasticity and gene loss underlying the evolution and divergence of two highly polyphagous and invasive Helicoverpa pest species. BMC Biology, 15 63: . doi:10.1186/s12915-017-0402-6

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Author Pearce, S. L.
Clarke, D. F.
East, P. D.
Elfekih, S.
Gordon, K. H. J.
Jermiin, L. S.
McGaughran, A.
Oakeshott, J. G.
Papanikolaou, A.
Perera, O. P.
Rane, R. V.
Richards, S.
Tay, W. T.
Walsh, T. K.
Anderson, A.
Anderson, C. J.
Asgari, S.
Board, P. G.
Bretschneider, A.
Campbell, P. M.
Chertemps, T.
Christeller, J. T.
Coppin, C. W.
Downes, S. J.
Duan, G.
Farnsworth, C. A.
Good, R. T.
Han, L. B.
Han, Y. C.
Hatje, K.
Horne, I.
Huang, Y. P.
Hughes, D. S. T.
Jacquin-Joly, E.
James, W.
Jhangiani, S.
Kollmar, M.
Kuwar, S. S.
Li, S.
Liu, N.-Y.
Maibeche, M. T.
Miller, J. R.
Montagne, N.
Perry, T.
Qu, J.
Songs, S. V.
Sutton, G. G.
Vogel, H.
Walenz, B. P.
Xu, W.
Zhang, H.-J.
Zou, Z.
Batterham, P.
Edwards, O. R.
Feyereisen, R.
Gibbs, R. A.
Heckel, D. G.
McGrath, A.
Robin, C.
Scherer, S. E.
Worley, K. C.
We, Y. D.
Title Genomic innovations, transcriptional plasticity and gene loss underlying the evolution and divergence of two highly polyphagous and invasive Helicoverpa pest species
Journal name BMC Biology   Check publisher's open access policy
ISSN 1741-7007
Publication date 2017-07-31
Year available 2017
Sub-type Article (original research)
DOI 10.1186/s12915-017-0402-6
Open Access Status DOI
Volume 15
Issue 63
Total pages 30
Place of publication London, United Kingdom
Publisher BioMed Central
Language eng
Subject 1305 Biotechnology
1315 Structural Biology
1105 Ecology, Evolution, Behavior and Systematics
1314 Physiology
1300 Biochemistry, Genetics and Molecular Biology
1100 Agricultural and Biological Sciences
1110 Plant Science
1309 Developmental Biology
1307 Cell Biology
Abstract Upon publication of the original article [1], it was noticed that Dr Papanicolaou's surname was spelt incorrectly. The correct spelling is "Papanicolaou", as shown in the author list of this erratum.
Formatted abstract
Helicoverpa armigera and Helicoverpa zea are major caterpillar pests of Old and New World agriculture, respectively. Both, particularly H. armigera, are extremely polyphagous, and H. armigera has developed resistance to many insecticides. Here we use comparative genomics, transcriptomics and resequencing to elucidate the genetic basis for their properties as pests.

We find that, prior to their divergence about 1.5 Mya, the H. armigera/H. zea lineage had accumulated up to more than 100 more members of specific detoxification and digestion gene families and more than 100 extra gustatory receptor genes, compared to other lepidopterans with narrower host ranges. The two genomes remain very similar in gene content and order, but H. armigera is more polymorphic overall, and H. zea has lost several detoxification genes, as well as about 50 gustatory receptor genes. It also lacks certain genes and alleles conferring insecticide resistance found in H. armigera. Non-synonymous sites in the expanded gene families above are rapidly diverging, both between paralogues and between orthologues in the two species. Whole genome transcriptomic analyses of H. armigera larvae show widely divergent responses to different host plants, including responses among many of the duplicated detoxification and digestion genes.

The extreme polyphagy of the two heliothines is associated with extensive amplification and neofunctionalisation of genes involved in host finding and use, coupled with versatile transcriptional responses on different hosts. H. armigera’s invasion of the Americas in recent years means that hybridisation could generate populations that are both locally adapted and insecticide resistant.
Keyword Armigera Hubner Lepidoptera
Heliothis-Virescens Lepidoptera
Maximum-Likelihood Phylogenies
Dna-Sequencing Data
Wild Host Plants
Rna-Seq Data
Insecticide Resistance
Zea Lepidoptera
Cotton Bollworm
Q-Index Code C1
Q-Index Status Provisional Code
Grant ID 2 R01 GM0//11/-04A1
FRST C06X0804
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
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School of Biological Sciences Publications
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Citation counts: TR Web of Science Citation Count  Cited 2 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 7 times in Scopus Article | Citations
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Created: Thu, 14 Sep 2017, 09:13:18 EST by Prof Sassan Asgari on behalf of School of Biological Sciences