CLINICAL ASSESSMENT OF RENAL FUNCTION IN THE DOG WITH A REDUCTION IN NEPHRON NUMBER

English, P. B., Filippich, L. J. and Thompson, H. L. (1980) CLINICAL ASSESSMENT OF RENAL FUNCTION IN THE DOG WITH A REDUCTION IN NEPHRON NUMBER. Australian Veterinary Journal, 56 7: 305-312. doi:10.1111/j.1751-0813.1980.tb05733.x


Author English, P. B.
Filippich, L. J.
Thompson, H. L.
Title CLINICAL ASSESSMENT OF RENAL FUNCTION IN THE DOG WITH A REDUCTION IN NEPHRON NUMBER
Journal name Australian Veterinary Journal   Check publisher's open access policy
ISSN 1751-0813
0005-0423
Publication date 1980-01-01
Sub-type Article (original research)
DOI 10.1111/j.1751-0813.1980.tb05733.x
Open Access Status Not yet assessed
Volume 56
Issue 7
Start page 305
End page 312
Total pages 8
Language eng
Subject 3400 Veterinary
Abstract The viewpoint presented is that, because compensatory functional adjustment of the residual nephrons occurs in chronic renal disease, reduction in nephron number usually exceeds 70% before a diagnosis is made. The case that earlier diagnoses are likely if laboratory medicine values are measured and interpreted with a maximum of efficiency is then made. The laboratory data more commonly used in practice for the clinical assessment of renal function in the dog are presented and some comparisons with findings in man are made. The information originates from clinical and experimental observations of the authors, as well as from a literature review. The laboratory data presented and discussed includes glomerular filtration rate and the clearance of nitrogenous waste (urea and creatinine), plasma protein concentration, plasma osmolality, renal concentrating capacity, and urinary constituents, particularly its protein concentration and sediment (centrifuge deposit). All parameters recommended for the clinical assessment of chronic renal failure are considered qualitatively, and some are also dealt with quantitatively. Copyright
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
 
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