Maternal age is a risk factor for caesarean section following induction of labour

Dunn, Liam, Kumar, Sailesh and Beckmann, Michael (2017) Maternal age is a risk factor for caesarean section following induction of labour. Australian & New Zealand Journal of Obstetrics & Gynaecology, 57 4: 426-431. doi:10.1111/ajo.12611

Author Dunn, Liam
Kumar, Sailesh
Beckmann, Michael
Title Maternal age is a risk factor for caesarean section following induction of labour
Journal name Australian & New Zealand Journal of Obstetrics & Gynaecology   Check publisher's open access policy
ISSN 1479-828X
Publication date 2017-08-01
Sub-type Article (original research)
DOI 10.1111/ajo.12611
Open Access Status Not yet assessed
Volume 57
Issue 4
Start page 426
End page 431
Total pages 6
Place of publication Richmond, VIC, Australia
Publisher Wiley-Blackwell Publishing Asia
Language eng
Subject 2729 Obstetrics and Gynaecology
Abstract Background: In Australia, more than 20% of women giving birth are 35 years or older. Advanced maternal age (AMA) is a risk factor for stillbirth, and many clinicians now recommend induction of labour (IOL) at around term gestation. The aim of this study is to determine if AMA is associated with emergency caesarean section (CS) following IOL. Methods: A retrospective cohort study was undertaken using routinely collected de-identified data. Live-born, singleton, cephalic, non-anomalous pregnancies undergoing IOL between 37 + 0 and 42 + 0 weeks were included. Previous CS and privately insured admission status were excluded. Mode of delivery was compared for women ≥38 years (AMA) and women <38 years. The primary outcome was birth by CS. Bivariate and multivariate logistic regression analyses were undertaken. Results: A total of 7459 women were included (≥38 years n = 718, 9.6%; <38 years n = 6741, 90.4%). AMA women had similar rates of unassisted vaginal births (OR 1.15, 95% CI 0.98–1.35, P = 0.080) and CS (OR 1.08, 95% CI 0.90–1.30, P = 0.407) but fewer instrumental deliveries (OR 0.69, 95% CI 0.55–0.87, P = 0.002) compared to women <38 years. When controlled for confounders, AMA was independently associated with a two-fold increase in birth by CS following IOL (adjusted OR 2.29; 95% CI 1.64–3.20; P < 0.001). There were no differences in neonatal outcomes. Conclusion: Following IOL, AMA was associated with a two-fold increased likelihood of birth by CS in both nulliparous and multiparous women. However, the majority of AMA women birthed vaginally. Clinicians may find this information useful when counselling older women who are undergoing term IOL.
Keyword Caesarean section
Maternal age
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

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