Trajectories of anxiety and health related quality of life during pregnancy

Schubert, K. Oliver, Air, Tracy, Clark, Scott R., Grzeskowiak, Luke E., Miller, Edward, Dekker, Gustaaf A., Baune, Bernhard T. and Clifton, Vicki L. (2017) Trajectories of anxiety and health related quality of life during pregnancy. PLoS One, 12 7: e0181149. doi:10.1371/journal.pone.0181149

Author Schubert, K. Oliver
Air, Tracy
Clark, Scott R.
Grzeskowiak, Luke E.
Miller, Edward
Dekker, Gustaaf A.
Baune, Bernhard T.
Clifton, Vicki L.
Title Trajectories of anxiety and health related quality of life during pregnancy
Journal name PLoS One   Check publisher's open access policy
ISSN 1932-6203
Publication date 2017-07-24
Sub-type Article (original research)
DOI 10.1371/journal.pone.0181149
Open Access Status DOI
Volume 12
Issue 7
Start page e0181149
Total pages 14
Place of publication San Francisco, CA, United States
Publisher Public Library of Science
Language eng
Subject 1300 Biochemistry, Genetics and Molecular Biology
1100 Agricultural and Biological Sciences
Abstract Anxiety and health related Quality of Life (HRQoL) have emerged as important mental health measures in obstetric care. Few studies have systematically examined the longitudinal trajectories of anxiety and HRQoL in pregnancy. Using a linear growth modeling strategy, we analyzed the course of State-Trait Anxiety Inventory (STAI)- and Short Form (36) Health Survey (SF-36) scores between the 12th and the 36th week of gestation, in a sample of 355 women. We additionally analyzed the impact of depressive symptoms and a chronic medical condition (asthma), on STAI and SF-36 trajectory curves. STAI scores remained stable throughout pregnancy. A previous history of anxiety increased the overall STAI scores. Asthma and depressive symptoms scores had no impact on the STAI trajectory. Physical SF-36 scores decreased over the course of pregnancy, whereas mental SF-36 trended towards improvement. Asthma reduced physical SF-36 overall. While high depressive symptoms decreased the overall mental SF-36, they were also significantly associated with mental SF-36 improvements over time. Anxiety symptoms are stable during pregnancy and are not modulated by depressive symptoms or asthma. Physical HRQoL declines in pregnancy. In contrast, mental HRQoL appears to improve, particularly in women with high initial levels of depressive symptoms.
Q-Index Code C1
Q-Index Status Provisional Code
Grant ID APP1041918
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Mater Research Institute-UQ (MRI-UQ)
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