Prostaglandins are important in thermoregulation of a reptile (Pogona vitticeps)

Seebacher, F. and Franklin, C. E. (2003) Prostaglandins are important in thermoregulation of a reptile (Pogona vitticeps). Proceedings of the Royal Society of London Series B - Biological Sciences, 270 SUPPL. 1: S50-S53. doi:10.1098/rsbl.2003.0007


Author Seebacher, F.
Franklin, C. E.
Title Prostaglandins are important in thermoregulation of a reptile (Pogona vitticeps)
Journal name Proceedings of the Royal Society of London Series B - Biological Sciences   Check publisher's open access policy
ISSN 0962-8452
1471-2954
Publication date 2003-01-01
Sub-type Article (original research)
DOI 10.1098/rsbl.2003.0007
Open Access Status Not yet assessed
Volume 270
Issue SUPPL. 1
Start page S50
End page S53
Total pages 4
Place of publication London
Publisher Royal Society of London
Collection year 2003
Language eng
Subject 270604 Comparative Physiology
780105 Biological sciences
06 Biological Sciences
Abstract The effectiveness of behavioural thermoregulation in reptiles is amplified by cardiovascular responses, particularly by differential rates of heart beat in response to heating and cooling (heart-rate hysteresis). Heart-rate hysteresis is ecologically important in most lineages of ectothermic reptile' and we demonstrate that heart-rate hysteresis in the lizard Pogona vitticeps is mediated by prostaglandins. In a control treatment (administration of saline), heart rates during heating were significantly faster than during cooling at any given body temperature. When cyclooxygenase 1 and 2 enzymes were inhibited, heart rates during heating were not significantly different from those during cooling. Administration of agonists showed that thromboxane B-2 did not have a significant effect on heart rate, but prostacyclin and prostaglandin F-2alpha caused a significant increase (3.5 and 13.6 beats min(-1), respectively) in heart rate compared with control treatments. We speculate that heart-rate hysteresis evolved as a thermoregulatory mechanism that may ultimately be controlled by neurally induced stimulation of nitric oxide production, or maybe via photolytically induced production of vitamin D.
Keyword Biology
thermoregulation
heart rate
prostaglandins
hysteresis
reptiles
Crocodile Crocodylus-porosus
Heart-rate
Barbata
Hysteresis
Q-Index Code C1

 
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Created: Wed, 15 Aug 2007, 12:11:19 EST