Reactions catalyzed by bacterial cytochromes P450

Cryle, M. J., Stok, J. E. and De Voss, J. J. (2003) Reactions catalyzed by bacterial cytochromes P450. Australian Journal of Chemistry, 56 8: 749-762. doi:10.1071/CH03040

Author Cryle, M. J.
Stok, J. E.
De Voss, J. J.
Title Reactions catalyzed by bacterial cytochromes P450
Journal name Australian Journal of Chemistry   Check publisher's open access policy
ISSN 0004-9425
Publication date 2003-01-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1071/CH03040
Open Access Status Not yet assessed
Volume 56
Issue 8
Start page 749
End page 762
Total pages 14
Place of publication Melbourne
Publisher CSIRO Publishing
Language eng
Subject C1
270108 Enzymes
780103 Chemical sciences
Abstract The cytochromes P450 are a large family of oxidative haemoproteins that are responsible for a wide variety of oxidative transformations in a variety of organisms. This review focuses upon the reactions catalyzed specifically by bacterial enzymes, which includes aliphatic hydroxylation, alkene epoxidation, aromatic hydroxylation, oxidative phenolic coupling, heteroatom oxidation and dealkylation, and multiple oxidations including C-C bond cleavage. The potential for the practical application of the oxidizing power of these enzymes is briefly discussed.
Keyword Chemistry, Multidisciplinary
Biosynthetic Gene-cluster
Polycyclic Aromatic-hydrocarbons
Mycobacterium-aurum Mo1
Herbicide-inducible Cytochromes-p-450
Nucleoside Antibiotic Nikkomycin
Tissue-selective Inhibitor
Site-specific Mutagenesis
Sp Strain He5
Sterol 14-alpha-demethylase
Q-Index Code C1

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Excellence in Research Australia (ERA) - Collection
2004 Higher Education Research Data Collection
School of Chemistry and Molecular Biosciences
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 80 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 86 times in Scopus Article | Citations
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Created: Wed, 15 Aug 2007, 11:55:58 EST