Estimates of global mortality attributable to smoking in 2000

Ezzati, M. and Lopez, A. D. (2003) Estimates of global mortality attributable to smoking in 2000. Lancet, 362 9387: 847-852. doi:10.1016/S0140-6736(03)14338-3

Author Ezzati, M.
Lopez, A. D.
Title Estimates of global mortality attributable to smoking in 2000
Journal name Lancet   Check publisher's open access policy
ISSN 0140-6736
Publication date 2003-09-13
Sub-type Article (original research)
DOI 10.1016/S0140-6736(03)14338-3
Open Access Status Not yet assessed
Volume 362
Issue 9387
Start page 847
End page 852
Total pages 6
Editor R. Horton
Place of publication United Kingdom
Publisher The Lancet Publishing Group
Language eng
Subject C1
321202 Epidemiology
730299 Public health not elsewhere classified
Abstract Background Smoking is a risk factor for several diseases and has been increasing in many developing countries. Our aim was to estimate global and regional mortality in 2000 caused by smoking, including an analysis of uncertainty. Methods Following the methods of Peto and colleagues, we used lung-cancer mortality as an indirect marker for accumulated smoking risk. Never-smoker lung-cancer mortality was estimated based on the household use of coal with poor ventilation. Relative risks were taken from the American Cancer Society Cancer Prevention Study, phase II, and the retrospective proportional mortality analysis of Liu and colleagues in China. Relative risks were corrected for confounding and extrapolation to other regions. Results We estimated that in 2000, 4.83 (uncertainty range 3.94-5.93) million premature deaths in the world were attributable to smoking; 2.41 (1.80-3.15) million in developing countries and 2.43 (2.13-2.78) million in industrialised countries. 3.84 million of these deaths were in men. The leading causes of death from smoking were cardiovascular diseases (1.69 million deaths), chronic obstructive pulmonary disease (0.97 million deaths), and lung cancer (0.85 million deaths). Interpretation Smoking was an important cause of global mortality in 2000. In view of the expected demographic and epidemiological transitions and current smoking patterns in the developing world, the health loss due to smoking will grow even larger unless effective interventions and policies that reduce smoking among men and prevent increases among women in developing countries are implemented.
Keyword Lung-cancer
Medicine, General & Internal
Q-Index Code C1
Institutional Status UQ

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Created: Wed, 15 Aug 2007, 11:55:42 EST