The importance of prolactin for initiation of lactation in the pregnant ewe

Gow C.B., Mc Dowell G.H. and Jenkinc G. (1983) The importance of prolactin for initiation of lactation in the pregnant ewe. Australian Journal of Biological Sciences, 36 4: 357-367. doi:10.1071/BI9830357

Author Gow C.B.
Mc Dowell G.H.
Jenkinc G.
Title The importance of prolactin for initiation of lactation in the pregnant ewe
Journal name Australian Journal of Biological Sciences   Check publisher's open access policy
ISSN 0004-9417
Publication date 1983-01-01
Sub-type Article (original research)
DOI 10.1071/BI9830357
Open Access Status
Volume 36
Issue 4
Start page 357
End page 367
Total pages 11
Language eng
Subject 1305 Biotechnology
2743 Reproductive Medicine
1103 Animal Science and Zoology
1312 Molecular Biology
2500 Materials Science
1311 Genetics
1310 Endocrinology
1309 Developmental Biology
Abstract A single injection of ergocryptine (0, 5 mg/kg liveweight) given to ewes O 5-20 days prepartum or two injections (05 mg/kg liveweight per injection) given c. 30 and 10 days prepartum reduced concentrations of plasma prolactin to negligible <5 ng/ml) values for 4 weeks after parturition, but did not affect concentrations of growth hormone and placental lactogen. Milking of treated ewes had no effect on concentrations of plasma prolactin during the first 4 weeks of lactation, but concentrations of growth hormone were increased during the 10-20 min period after milking. The half-life of prolactin in plasma was estimated as 21 min. In spite of the dramatic effect of ergocryptine on plasma prolactin all treated ewes secreted copious quantities of milk of normal composition. Mean daily yields of ewes treated with ergocryptine were not significantly different (P > 0'05) from those of untreated control ewes, but the mean s.e.m. of total milk production over the first 3 weeks of lactation for ergocryptine-treated ewes was significantly lower (P < 0'05) than that of control ewes (9.5±1.11 v. 14.1±1.20 kg milk). The results suggest that prolactin is not an essential component of the lactogenic and galactopoietic complexes of hormones in the ewe.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: Scopus Import - Archived
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