The calcium-cancer signalling nexus

Monteith, Gregory R., Prevarskaya, Natalia and Roberts-Thomson, Sarah J. (2017) The calcium-cancer signalling nexus. Nature Reviews Cancer, 17 6: 367-380. doi:10.1038/nrc.2017.18

Author Monteith, Gregory R.
Prevarskaya, Natalia
Roberts-Thomson, Sarah J.
Title The calcium-cancer signalling nexus
Journal name Nature Reviews Cancer   Check publisher's open access policy
ISSN 1474-1768
Publication date 2017-06-01
Year available 2017
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1038/nrc.2017.18
Open Access Status Not yet assessed
Volume 17
Issue 6
Start page 367
End page 380
Total pages 14
Place of publication London, United Kingdom
Publisher Nature Publishing Group
Language eng
Abstract The calcium signal is a powerful and multifaceted tool by which cells can achieve specific outcomes. Cellular machinery important in tumour progression is often driven or influenced by changes in calcium ions; in some cases this regulation occurs within spatially defined regions. Over the past decade there has been a deeper understanding of how calcium signalling is remodelled in some cancers and the consequences of calcium signalling on key events such as proliferation, invasion and sensitivity to cell death. Specific calcium signalling pathways have also now been identified as playing important roles in the establishment and maintenance of multidrug resistance and the tumour microenvironment.
Keyword Oncology
Q-Index Code C1
Q-Index Status Provisional Code
Grant ID 1079671
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Mater Research Institute-UQ (MRI-UQ)
HERDC Pre-Audit
School of Pharmacy Publications
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Citation counts: TR Web of Science Citation Count  Cited 11 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 16 times in Scopus Article | Citations
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