Neurospectroscopy: the past, present and future

Mountford, Carolyn E., Stanwell, Peter, Lin, Alexander, Ramadan, Saadallah and Ross, Brian (2010) Neurospectroscopy: the past, present and future. Chemical Reviews, 110 5: 3060-3086. doi:10.1021/cr900250y

Author Mountford, Carolyn E.
Stanwell, Peter
Lin, Alexander
Ramadan, Saadallah
Ross, Brian
Title Neurospectroscopy: the past, present and future
Journal name Chemical Reviews   Check publisher's open access policy
ISSN 0009-2665
Publication date 2010-05-12
Year available 2010
Sub-type Article (original research)
DOI 10.1021/cr900250y
Open Access Status Not yet assessed
Volume 110
Issue 5
Start page 3060
End page 3086
Total pages 27
Place of publication Washington, DC, United States
Publisher American Chemical Society
Language eng
Abstract Neurospectroscopy with respect to its past, present and future has been reported. It is helpful to understand the biochemical relevance of each of the major resonances in the brain spectra. Lactate is seen in the spectrum as a doublet at 1.33 ppm. Healthy tissues do not have sufficient lactate to be detectable by MRS. Neurospectroscopy provides information on brain constituents. Pattern recognition blends pattern recognition techniques and multivariate statistical analysis with solid, comprehensive software engineering practices. Neurospectroscopy offers a window into the chemistry of the human brain, reporting on normal mechanisms as well as the changes that occur with degeneration, disease, pain, cancer, and infection. Alzheimer's disease can now be identified much earlier than before offering earlier management before the disease progresses. The long-term effect of shaken baby syndrome and traumatic brain injury can be gauged by neurospectroscopy.
Keyword Chemistry, Multidisciplinary
Q-Index Code C1
Q-Index Status Provisional Code
Grant ID DP0663987
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Centre for Advanced Imaging Publications
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Citation counts: TR Web of Science Citation Count  Cited 57 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 62 times in Scopus Article | Citations
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