Prophylactic swallow therapy for patients with head and neck cancer undergoing chemoradiotherapy: a randomized trial

Messing, Barbara Pisano, Ward, Elizabeth C., Lazarus, Cathy L., Kim, Melissa, Zhou, Xian, Silinonte, Jessica, Gold, Dorothy, Harrer, Karen, Ulmer, Karen, Merritt, Samantha, Neuner, Geoffrey, Levine, Marshall, Blanco, Ray, Saunders, John and Califano, Joseph (2017) Prophylactic swallow therapy for patients with head and neck cancer undergoing chemoradiotherapy: a randomized trial. Dysphagia, 32 4: 487-500. doi:10.1007/s00455-017-9790-6


Author Messing, Barbara Pisano
Ward, Elizabeth C.
Lazarus, Cathy L.
Kim, Melissa
Zhou, Xian
Silinonte, Jessica
Gold, Dorothy
Harrer, Karen
Ulmer, Karen
Merritt, Samantha
Neuner, Geoffrey
Levine, Marshall
Blanco, Ray
Saunders, John
Califano, Joseph
Title Prophylactic swallow therapy for patients with head and neck cancer undergoing chemoradiotherapy: a randomized trial
Journal name Dysphagia   Check publisher's open access policy
ISSN 1432-0460
0179-051X
Publication date 2017-04-25
Sub-type Article (original research)
DOI 10.1007/s00455-017-9790-6
Open Access Status DOI
Volume 32
Issue 4
Start page 487
End page 500
Total pages 14
Place of publication New York, NY, United States
Publisher Springer New York LLC
Language eng
Subject 2733 Otorhinolaryngology
2715 Gastroenterology
3616 Speech and Hearing
Abstract Evidence supporting prophylactic swallow exercises for patients with head and neck cancer (HNC) has not been universally demonstrated. This RCT examined diet level, feeding tube use, swallow function, and quality of life (QOL) of patients undergoing chemoradiotherapy who performed prophylactic swallowing exercises. Sixty HNC patients were randomized into exercise versus control groups. Swallowing, oromotor, toxicity, and QOL data were recorded (baseline, 3, 6, 12, 24 months). Physiological swallow function was examined at baseline and 3 months. Swallow exercises were completed twice daily. Oral intake at 3 months was 10% better in the exercise group, which was not statistically significant (p = 0.49). Significant (p < 0.05) differences in secondary outcomes including oromotor function, pharyngeal impairment, oral pharyngeal swallow efficiency, and incisal opening were noted at early time points (3–6 months) in the exercise group. Possible positive early improvements in swallow function are associated with swallowing exercises, although these improvements are not significant longer term.
Formatted abstract
Evidence supporting prophylactic swallow exercises for patients with head and neck cancer (HNC) has not been universally demonstrated. This RCT examined diet level, feeding tube use, swallow function, and quality of life (QOL) of patients undergoing chemoradiotherapy who performed prophylactic swallowing exercises. Sixty HNC patients were randomized into exercise versus control groups. Swallowing, oromotor, toxicity, and QOL data were recorded (baseline, 3, 6, 12, 24 months). Physiological swallow function was examined at baseline and 3 months. Swallow exercises were completed twice daily. Oral intake at 3 months was 10% better in the exercise group, which was not statistically significant (p = 0.49). Significant (p < 0.05) differences in secondary outcomes including oromotor function, pharyngeal impairment, oral pharyngeal swallow efficiency, and incisal opening were noted at early time points (3–6 months) in the exercise group. Possible positive early improvements in swallow function are associated with swallowing exercises, although these improvements are not significant longer term.
Keyword Chemoradiation
Dysphagia
Prophylactic exercises
Quality of life
Swallowing
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Health and Rehabilitation Sciences Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 0 times in Thomson Reuters Web of Science Article
Scopus Citation Count Cited 2 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 23 May 2017, 00:05:21 EST by Web Cron on behalf of Learning and Research Services (UQ Library)