From marine venoms to drugs: efficiently supported by a combination of transcriptomics and proteomics

Xie, Bing, Huang, Yuang, Baumann, Kate, Fry, Bryan Grieg and Shi, Qiong (2017) From marine venoms to drugs: efficiently supported by a combination of transcriptomics and proteomics. Marine Drugs, 15 4: . doi:10.3390/md15040103


Author Xie, Bing
Huang, Yuang
Baumann, Kate
Fry, Bryan Grieg
Shi, Qiong
Title From marine venoms to drugs: efficiently supported by a combination of transcriptomics and proteomics
Journal name Marine Drugs   Check publisher's open access policy
ISSN 1660-3397
Publication date 2017-04-01
Year available 2017
Sub-type Critical review of research, literature review, critical commentary
DOI 10.3390/md15040103
Open Access Status DOI
Volume 15
Issue 4
Total pages 10
Place of publication Basel, Switzerland
Publisher MDPI AG
Language eng
Abstract The potential of marine natural products to become new drugs is vast; however, research is still in its infancy. The chemical and biological diversity of marine toxins is immeasurable and as such an extraordinary resource for the discovery of new drugs. With the rapid development of next-generation sequencing (NGS) and liquid chromatography–tandem mass spectrometry (LC-MS/MS), it has been much easier and faster to identify more toxins and predict their functions with bioinformatics pipelines, which pave the way for novel drug developments. Here we provide an overview of related bioinformatics pipelines that have been supported by a combination of transcriptomics and proteomics for identification and function prediction of novel marine toxins.
Keyword Marine toxins
Database
Transcriptome
Proteome
Venomics
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: HERDC Pre-Audit
School of Biological Sciences Publications
 
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