Dietary patterns and clinical outcomes in chronic kidney disease: the CKD.QLD nutrition study

Wai, Shu Ning, Kelly, Jaimon T., Johnson, David W. and Campbell, Katrina L. (2017) Dietary patterns and clinical outcomes in chronic kidney disease: the CKD.QLD nutrition study. Journal of Renal Nutrition, 27 3: 175-182. doi:10.1053/j.jrn.2016.10.005

Author Wai, Shu Ning
Kelly, Jaimon T.
Johnson, David W.
Campbell, Katrina L.
Title Dietary patterns and clinical outcomes in chronic kidney disease: the CKD.QLD nutrition study
Journal name Journal of Renal Nutrition   Check publisher's open access policy
ISSN 1051-2276
Publication date 2017-05-01
Year available 2016
Sub-type Article (original research)
DOI 10.1053/j.jrn.2016.10.005
Open Access Status Not yet assessed
Volume 27
Issue 3
Start page 175
End page 182
Total pages 8
Place of publication Maryland Heights, MO, United States
Publisher W.B. Saunders
Language eng
Formatted abstract
Objective: Emerging evidence suggests that dietary patterns are associated with survival in people with chronic kidney disease (CKD). This study evaluated the relationship between dietary habits and renal-related clinical outcomes in an established CKD cohort.

Design: Prospective cohort study.

Setting: Three outpatient nephrology clinics in Queensland, Australia.

Subjects: A total of 145 adult patients with Stage 3 or 4 CKD (estimated glomerular filtration rate 15-59 mL/minute/1.73 m2).

Intervention: Dietary intake was measured using 24-hour recall and the HeartWise Dietary Habits Questionnaire (DHQ), which evaluates 10 components of dietary patterns in relation to cooking habits and intake of food groups.

Main Outcome Measure: The primary outcome was a composite end point of all-cause mortality, commencement of dialysis, and doubling of serum creatinine. Secondary outcome was all-cause mortality alone. Multivariate cox regression analyses calculated hazard ratios (HRs) for associations between DHQ domains and occurrence of composite outcome and adjusted for confounders, including comorbidities and renal function.

Results: Over a median follow-up of 36 months, 32% (n = 47) reached the composite end point, of which 21% died (n = 30). Increasing DHQ score was associated with a lower risk of the composite end point with increasing intake of fruits and vegetables (HR: 0.61; 95% CI, 0.39-0.94) and limiting alcohol consumption (HR, 0.79; 95% CI: 0.65-0.96). For the secondary outcome of all-cause mortality, there was a significant association with adequate intake of fruits and vegetables (HR: 0.35; 95% CI, 0.15-0.83).

Conclusion: Healthy dietary patterns consisting of adequate fruits and vegetables and limited alcohol consumption are associated with a delay in CKD progression and improved survival in patients with Stage 3 or 4 CKD.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Clinical Medicine Publications
Admin Only - School of Clinical Medicine
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 2 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 3 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 09 May 2017, 00:23:47 EST by System User on behalf of Learning and Research Services (UQ Library)