Impact of in-sewer degradation of pharmaceutical and personal care products (PPCPs) population markers on a population model

O'Brien, Jake William, Banks, Andrew Philip William, Novic, Andrew Joseph, Mueller, Jochen F., Jiang, Guangming, Ort, Christoph, Eaglesham, Geoff, Yuan, Zhiguo and Thai, Phong K. (2017) Impact of in-sewer degradation of pharmaceutical and personal care products (PPCPs) population markers on a population model. Environmental Science and Technology, 51 7: 3816-3823. doi:10.1021/acs.est.6b02755


Author O'Brien, Jake William
Banks, Andrew Philip William
Novic, Andrew Joseph
Mueller, Jochen F.
Jiang, Guangming
Ort, Christoph
Eaglesham, Geoff
Yuan, Zhiguo
Thai, Phong K.
Title Impact of in-sewer degradation of pharmaceutical and personal care products (PPCPs) population markers on a population model
Journal name Environmental Science and Technology   Check publisher's open access policy
ISSN 0013-936X
1520-5851
Publication date 2017-04-04
Year available 2017
Sub-type Article (original research)
DOI 10.1021/acs.est.6b02755
Open Access Status Not yet assessed
Volume 51
Issue 7
Start page 3816
End page 3823
Total pages 8
Place of publication Washington, DC, United States
Publisher American Chemical Society
Language eng
Subject 1600 Chemistry
2304 Environmental Chemistry
Abstract A key uncertainty of wastewater-based epidemiology is the size of the population which contributed to a given wastewater sample. We previously developed and validated a Bayesian inference model to estimate population size based on 14 population markers which: (1) are easily measured and (2) have mass loads which correlate with population size. However, the potential uncertainty of the model prediction due to in-sewer degradation of these markers was not evaluated. In this study, we addressed this gap by testing their stability under sewer conditions and assessed whether degradation impacts the model estimates. Five markers, which formed the core of our model, were stable in the sewers while the others were not. Our evaluation showed that the presence of unstable population markers in the model did not decrease the precision of the population estimates providing that stable markers such as acesulfame remained in the model. However, to achieve the minimum uncertainty in population estimates, we propose that the core markers to be included in population models for other sites should meet two additional criteria: (3) negligible degradation in wastewater to ensure the stability of chemicals during collection; and (4) < 10% in-sewer degradation could occur during the mean residence time of the sewer network.
Keyword Engineering, Environmental
Environmental Sciences
Engineering
Environmental Sciences & Ecology
Q-Index Code C1
Q-Index Status Provisional Code
Grant ID DP150100645
FT120100546
Institutional Status UQ

 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 4 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 4 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Mon, 08 May 2017, 01:00:44 EST by Web Cron on behalf of Learning and Research Services (UQ Library)