Muscle-specific regulation of tropomyosin gene expression and myofibrillogenesis differs among muscle systems examined at metamorphosis of the gastropod Haliotis rufescens

Degnan, BM, Degnan, SM and Morse, DE (1997) Muscle-specific regulation of tropomyosin gene expression and myofibrillogenesis differs among muscle systems examined at metamorphosis of the gastropod Haliotis rufescens. Development Genes And Evolution, 206 7: 464-471. doi:10.1007/s004270050076


Author Degnan, BM
Degnan, SM
Morse, DE
Title Muscle-specific regulation of tropomyosin gene expression and myofibrillogenesis differs among muscle systems examined at metamorphosis of the gastropod Haliotis rufescens
Journal name Development Genes And Evolution   Check publisher's open access policy
ISSN 0949-944X
Publication date 1997-01-01
Sub-type Article (original research)
DOI 10.1007/s004270050076
Volume 206
Issue 7
Start page 464
End page 471
Total pages 8
Language eng
Abstract The spatial and temporal association of muscle-specific tropomyosin gene expression, and myofibril assembly and degradation during metamorphosis is analyzed in the gastropod mollusc. Haliotis rufescens. Metamorphosis of tile planktonic larva to the benthic juvenile includes rearrangement and atrophy of specific larval muscles, and biogenesis of the new juvenile muscle system. The major muscle of the larva - the larval retractor muscle - reorganizes at metamorphosis, with two suites of cells having different fates. The ventral cells degenerate, while the dorsal cells become part of the developing juvenile mantle musculature. Prior to these changes in myofibrillar structure, tropomyosin mRNA prevalence declines until undetectable in the ventral cells, while increasing markedly in the dorsal cells. In the foot muscle and right shell muscle, tropomyosin mRNA levels remain relatively stable, even trough myofibril content increases. In a population of median mesoderm cells destined to form de novo the major muscle of the juvenile and adult (the columellar muscle), tropomyosin expression is initiated at 45 h after induction of metamorphosis. Myofibrillar filamentous actin is not detected in these cells until about 7 days later. Given that patterns of tropomyosin mRNA accumulation in relation to myofibril assembly and disassembly differ significantly among the four major muscle systems examined, we suggest that different regulatory mechanisms, probably operating at both transcriptional and post-transcriptional levels, control the biogenesis and atrophy of different larval and postlarval muscles at metamorphosis.
Keyword Cell Biology
Evolutionary Biology
Developmental Biology
Abalone
Competence
In Situ Hybridization
Larva
Muscle Cell
Skeletal-muscle
Drosophila-melanogaster
Biomphalaria-glabrata
Contractile Protein
Schistosoma-mansoni
Alpha-tropomyosin
Human-fibroblasts
Mouse Muscle
Sequence
Larvae
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Biological Sciences Publications
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 37 times in Thomson Reuters Web of Science Article | Citations
Google Scholar Search Google Scholar
Created: Tue, 14 Aug 2007, 02:46:22 EST