Left ventricular flow propagation velocity measurement: is it cast in stone?

Chan, Bee Ting, Yeoh, Hak Koon, Liew, Yih Miin, Aziz, Yang Faridah Abdul, Sridhar, Ganiga Srinivasaiah, Hamilton-Craig, Christian, Platts, David and Lim, Einly (2017) Left ventricular flow propagation velocity measurement: is it cast in stone?. Medical and Biological Engineering and Computing, 1-11. doi:10.1007/s11517-017-1639-5

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Author Chan, Bee Ting
Yeoh, Hak Koon
Liew, Yih Miin
Aziz, Yang Faridah Abdul
Sridhar, Ganiga Srinivasaiah
Hamilton-Craig, Christian
Platts, David
Lim, Einly
Title Left ventricular flow propagation velocity measurement: is it cast in stone?
Journal name Medical and Biological Engineering and Computing   Check publisher's open access policy
ISSN 1741-0444
0140-0118
Publication date 2017-03-20
Year available 2017
Sub-type Article (original research)
DOI 10.1007/s11517-017-1639-5
Open Access Status File (Author Post-print)
Start page 1
End page 11
Total pages 11
Place of publication Heidelberg, Germany
Publisher Springer
Collection year 2018
Language eng
Formatted abstract
This study aims to investigate the measurement of left ventricular flow propagation velocity, Vp, using phase contrast magnetic resonance imaging and to assess the discrepancies resulting from inflow jet direction and individual left ventricular size. Three Vp measuring techniques, namely non-adaptive (NA), adaptive positions (AP) and adaptive vectors (AV) method, were suggested and compared. We performed the comparison on nine healthy volunteers and nine post-infarct patients at four measurement positions, respectively, at one-third, one-half, two-thirds and the conventional 4 cm distances from the mitral valve leaflet into the left ventricle. We found that the Vp measurement was affected by both the inflow jet direction and measurement positions. Both NA and AP methods overestimated Vp, especially in dilated left ventricles, while the AV method showed the strongest correlation with the isovolumic relaxation myocardial strain rate (r = 0.53, p < 0.05). Using the AV method, notable difference in mean Vp was also observed between healthy volunteers and post-infarct patients at positions of: one-half (81 ± 31 vs. 58 ± 25 cm/s), two-thirds (89 ± 32 vs. 45 ± 15 cm/s) and 4 cm (98 ± 23 vs. 47 ± 13 cm/s) distances. The use of AV method and measurement position at one-half distance was found to be the most suitable method for assessing diastolic dysfunction given varying left ventricular sizes and inflow jet directions.
Keyword Flow propagation velocity
Vp
LV relaxation
Magnetic resonance
Diastolic dysfunction
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
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