Echocardiographic assessment of degenerative mitral stenosis: a diagnostic challenge of an Eemerging cardiac disease

Oktay, Ahmet Afsin, Gilliland, Yvonne E., Lavie, Carl J., Ramee, Stephen J., Parrino, Patrick E., Bates, Michael, Shah, Sangeeta, Cash, Michael E., Dinshaw, Homeyar and Qamruddin, Salima (2017) Echocardiographic assessment of degenerative mitral stenosis: a diagnostic challenge of an Eemerging cardiac disease. Current Problems in Cardiology, 42 3: 71-100. doi:10.1016/j.cpcardiol.2017.01.002


Author Oktay, Ahmet Afsin
Gilliland, Yvonne E.
Lavie, Carl J.
Ramee, Stephen J.
Parrino, Patrick E.
Bates, Michael
Shah, Sangeeta
Cash, Michael E.
Dinshaw, Homeyar
Qamruddin, Salima
Title Echocardiographic assessment of degenerative mitral stenosis: a diagnostic challenge of an Eemerging cardiac disease
Journal name Current Problems in Cardiology   Check publisher's open access policy
ISSN 1535-6280
0146-2806
Publication date 2017-03-01
Sub-type Article (original research)
DOI 10.1016/j.cpcardiol.2017.01.002
Open Access Status Not yet assessed
Volume 42
Issue 3
Start page 71
End page 100
Total pages 30
Place of publication Philadelphia, PA, United States
Publisher Mosby
Collection year 2018
Language eng
Abstract Degenerative mitral stenosis (DMS) is characterized by decreased mitral valve (MV) orifice area and increased transmitral pressure gradient due to chronic noninflammatory degeneration and subsequent calcification of the fibrous mitral annulus and the MV leaflets. The “true” prevalence of DMS in the general population is unknown. DMS predominantly affects elderly individuals, many of whom have multiple other comorbidities. Transcatheter MV replacement techniques, although their long-term outcomes are yet to be tested, have been gaining popularity and may emerge as more effective and relatively safer treatment option for patients with DMS. Echocardiography is the primary imaging modality for evaluation of DMS and related hemodynamic abnormalities such as increased transmitral pressure gradient and pulmonary arterial pressure. Classic echocardiographic techniques used for evaluation of mitral stenosis (pressure half time, proximal isovelocity surface area, continuity equation, and MV area planimetry) lack validation for DMS. Direct planimetry with 3-dimensional echocardiography and color flow Doppler is a reasonable technique for determining MV area in DMS. Cardiac computed tomography is an essential tool for planning potential interventions or surgeries for DMS. This article reviews the current concepts on mitral annular calcification and its role in DMS. We then discuss the epidemiology, natural history, differential diagnosis, mechanisms, and echocardiographic assessment of DMS.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Medicine Publications
 
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