Polishing the tarnished silver bullet: the quest for new antibiotics

Blaskovich, Mark A. T., Butler, Mark S. and Cooper, Matthew A. (2017) Polishing the tarnished silver bullet: the quest for new antibiotics. Antimicrobial Resistance, 61 1: 103-114. doi:10.1042/EBC20160077


Author Blaskovich, Mark A. T.
Butler, Mark S.
Cooper, Matthew A.
Title Polishing the tarnished silver bullet: the quest for new antibiotics
Journal name Antimicrobial Resistance   Check publisher's open access policy
ISSN 0071-1365
1744-1358
Publication date 2017-03-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1042/EBC20160077
Open Access Status Not yet assessed
Volume 61
Issue 1
Start page 103
End page 114
Total pages 12
Place of publication London, United Kingdom
Publisher Portland Press
Collection year 2018
Language eng
Abstract We are facing a potential catastrophe of untreatable bacterial infections, driven by the inexorable rise of extensively drug-resistant bacteria, coupled with a market failure of pharmaceutical and biotech companies to deliver new therapeutic options. While global recognition of the problem is finally apparent, solutions are still a long way from being implemented. In addition to drug stewardship programmes and better diagnostics, new antibiotics are desperately needed. The question remains as to how to achieve this goal. This review will examine the different strategies being applied to discover new antibiotics.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: HERDC Pre-Audit
Institute for Molecular Bioscience - Publications
 
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