Co-option and de novo gene evolution underlie molluscan shell diversity

Aguilera, Felipe, McDougall, Carmel and Degnan, Bernard M. (2017) Co-option and de novo gene evolution underlie molluscan shell diversity. Molecular Biology and Evolution, 34 4: 779-792. doi:10.1093/molbev/msw294


Author Aguilera, Felipe
McDougall, Carmel
Degnan, Bernard M.
Title Co-option and de novo gene evolution underlie molluscan shell diversity
Journal name Molecular Biology and Evolution   Check publisher's open access policy
ISSN 0737-4038
1537-1719
Publication date 2017-04-01
Sub-type Article (original research)
DOI 10.1093/molbev/msw294
Open Access Status DOI
Volume 34
Issue 4
Start page 779
End page 792
Total pages 14
Place of publication Cary, NC, United States
Publisher Oxford University Press
Collection year 2018
Language eng
Formatted abstract
Molluscs fabricate shells of incredible diversity and complexity by localized secretions from the dorsal epithelium of the mantle. Although distantly related molluscs express remarkably different secreted gene products, it remains unclear if the evolution of shell structure and pattern is underpinned by the differential co-option of conserved genes or the integration of lineage-specific genes into the mantle regulatory program. To address this, we compare the mantle transcriptomes of 11 bivalves and gastropods of varying relatedness. We find that each species, including four Pinctada (pearl oyster) species that diverged within the last 20 Ma, expresses a unique mantle secretome. Lineage- or species-specific genes comprise a large proportion of each species’ mantle secretome. A majority of these secreted proteins have unique domain architectures that include repetitive, low complexity domains (RLCDs), which evolve rapidly, and have a proclivity to expand, contract and rearrange in the genome. There are also a large number of secretome genes expressed in the mantle that arose before the origin of gastropods and bivalves. Each species expresses a unique set of these more ancient genes consistent with their independent co-option into these mantle gene regulatory networks. From this analysis, we infer lineage-specific secretomes underlie shell diversity, and include both rapidly evolving RLCD-containing proteins, and the continual recruitment and loss of both ancient and recently evolved genes into the periphery of the regulatory network controlling gene expression in the mantle epithelium.
Keyword Mantle secretome
Co-option
Lineage-specific novelties
Bivalve
Gastropod
Shell formation
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Biological Sciences Publications
 
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