High prevalence of sessile serrated adenomas in contemporary outpatient colonoscopy practice

Bettington, Mark, Walker, Neal, Rahman, Tony, Vandeleur, Ann, Whitehall, Vicki, Leggett, Barbara and Croese, John (2017) High prevalence of sessile serrated adenomas in contemporary outpatient colonoscopy practice. Internal Medicine Journal, 47 3: 318-323. doi:10.1111/imj.13329

Author Bettington, Mark
Walker, Neal
Rahman, Tony
Vandeleur, Ann
Whitehall, Vicki
Leggett, Barbara
Croese, John
Title High prevalence of sessile serrated adenomas in contemporary outpatient colonoscopy practice
Journal name Internal Medicine Journal   Check publisher's open access policy
ISSN 1445-5994
Publication date 2017-03-01
Sub-type Article (original research)
DOI 10.1111/imj.13329
Open Access Status Not yet assessed
Volume 47
Issue 3
Start page 318
End page 323
Total pages 6
Place of publication Richmond, VIC, Australia
Publisher Wiley-Blackwell Publishing Asia
Collection year 2018
Language eng
Formatted abstract
Background: Sessile serrated adenomas (SSA) are the polyp precursor of 15–20% of colorectal carcinomas. There is debate about their prevalence and increasing discussion about the need for a serrated polyp detection rate as a quality indicator for colonoscopy.

Aims: To assess the prevalence of SSA at an outpatient gastroenterology service.

Methods: This is a retrospective study of an unselected consecutive series of patients who had an outpatient colonoscopy between April 2013 and May 2014. The colonoscopy reports were reviewed to identify age, gender, indication for procedure, completion, withdrawal time, adequacy of bowel preparation, number, size and location of polyps. The pathology of all polyps was centrally reviewed by a gastrointestinal pathologist.

Results: A total of 707 patients underwent colonoscopy within the study period. The mean age of the cohort was 58 years, and 50.6% were female. Polyp(s) were identified in 66.5% of patients. The SSA detection rate was 20.1%, and the adenoma detection rate was 48.0%. SSA detection was associated with longer withdrawal times. Conventional adenoma detection was associated with older age, male gender, longer withdrawal time and a positive faecal occult blood test result.

Conclusion: SSA are highly prevalent in an unselected series of patients attending a gastroenterology outpatient department. Identifying and removing these polyps may help prevent interval colorectal carcinoma. This result may serve as a benchmark for a high-quality colonoscopy service.
Keyword Colonoscopy
Colorectal cancer
Sessile serrated adenoma
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
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