Mortality in individuals with disruptive behavior disorders diagnosed by specialist services – a nationwide cohort study

Scott, James G., Giortz Pedersen, Marianne, Erskine, Holly E. , Bikic, Aida, Demontis, Ditte, McGrath, John J. and Dalsgaard, Soren (2017) Mortality in individuals with disruptive behavior disorders diagnosed by specialist services – a nationwide cohort study. Psychiatry Research, 251 255-260. doi:10.1016/j.psychres.2017.02.029


Author Scott, James G.
Giortz Pedersen, Marianne
Erskine, Holly E.
Bikic, Aida
Demontis, Ditte
McGrath, John J.
Dalsgaard, Soren
Title Mortality in individuals with disruptive behavior disorders diagnosed by specialist services – a nationwide cohort study
Journal name Psychiatry Research   Check publisher's open access policy
ISSN 1872-7123
0165-1781
Publication date 2017-05-01
Sub-type Article (original research)
DOI 10.1016/j.psychres.2017.02.029
Open Access Status Not yet assessed
Volume 251
Start page 255
End page 260
Total pages 6
Place of publication E Park, Shannon, Clare Ireland
Publisher Elsevier Ireland
Collection year 2018
Language eng
Abstract Disruptive behavior disorders (DBDs), inclusive of oppositional defiant disorder (ODD) and conduct disorder (CD), are associated with outcomes likely to increase risk of mortality. Using Danish National Registers, a total of 1.92 million individuals including 9495 individuals with DBDs diagnosed by specialist services were followed from their first birthday to 2013. Those with and without DBDs were compared using mortality rate ratios (MRRs) estimated using Poisson regression and adjusted for calendar period, age, sex, family history of psychiatric disorders, maternal age at time of birth, paternal age at time of birth, parental education status, and parental employment status. Over the course of follow up, which totalled 24.9 million person-years, 5580 cohort members died including 78 individuals with DBDs. The mortality rate per 10,000 person-years was 9.66 for individuals with DBDs compared to 2.22 for those with no diagnosis. This corresponded to a fully adjusted MRR of 2.57 (95% confidence interval 2.04–3.20). Comorbid substance use disorder and attention-deficit/hyperactivity disorder resulted in the highest MRR across all categories. These findings demonstrate the excess mortality associated with DBDs.
Keyword Conduct disorder
Deaths
Disruptive behavior disorders
Epidemiology
Mortality
Oppositional defiant disorder
Registries
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

 
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