Immunological biomarkers of tuberculosis

Walzl, Gerhard, Ronacher, Katharina, Hanekom, Willem, Scriba, Thomas J. and Zumla, Alimuddin (2011) Immunological biomarkers of tuberculosis. Nature Reviews Immunology, 11 5: 343-354. doi:10.1038/nri2960

Author Walzl, Gerhard
Ronacher, Katharina
Hanekom, Willem
Scriba, Thomas J.
Zumla, Alimuddin
Title Immunological biomarkers of tuberculosis
Journal name Nature Reviews Immunology   Check publisher's open access policy
ISSN 1474-1733
Publication date 2011-05-01
Year available 2011
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1038/nri2960
Open Access Status Not yet assessed
Volume 11
Issue 5
Start page 343
End page 354
Total pages 12
Place of publication London, United Kingdom
Publisher Nature Publishing Group
Language eng
Formatted abstract
Currently there are no sufficiently validated biomarkers to aid the evaluation of new tuberculosis vaccine candidates, the improvement of tuberculosis diagnostics or the development of more effective and shorter treatment regimens. To date, the detection of Mycobacterium tuberculosis or its products has not been able to adequately address these needs. Understanding the interplay between the host immune system and M. tuberculosis may provide a platform for the identification of suitable biomarkers, through both unbiased and targeted hypothesis-driven approaches. Here, we review immunological markers, their relation to M. tuberculosis infection stages and their potential use in the fight against tuberculosis.
Keyword Immunology
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: Mater Research Institute-UQ (MRI-UQ)
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Created: Thu, 16 Feb 2017, 11:35:56 EST by Johanna Barclay on behalf of Mater Research Institute-UQ