Renal denervation for resistant hypertension

Reilly, John P. and White, Christopher J. (2016) Renal denervation for resistant hypertension. Progress in Cardiovascular Diseases, 59 3: 295-302. doi:10.1016/j.pcad.2016.10.003

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Author Reilly, John P.
White, Christopher J.
Title Renal denervation for resistant hypertension
Journal name Progress in Cardiovascular Diseases   Check publisher's open access policy
ISSN 1873-1740
Publication date 2016-11-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.pcad.2016.10.003
Open Access Status File (Author Post-print)
Volume 59
Issue 3
Start page 295
End page 302
Total pages 8
Place of publication Maryland Heights, MO, United States
Publisher W.B. Saunders
Language eng
Subject 2705 Cardiology and Cardiovascular Medicine
Abstract Renal denervation as a treatment for hypertension (HTN) has been shown to be effective as a surgical procedure. Over the past 10 years, an endovascular approach to replicate the results of surgical splanchnicectomy has been investigated to replace this surgical procedure with a less invasive procedure with lower morbidity. Several devices and procedures have been developed, including a non-invasive strategy. We review the improvement of HTN in clinical trials of these devices as well as the shortcomings of these studies. Thus far, these trials have been unable to prove that these renal denervation strategies are superior to medical therapy alone, but we look forward to further randomized, double blinded trials of current systems that can effectively achieve denervation to reduce the risk of HTN.
Keyword Anti-hypertensive agents
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
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