Unraveling the microbial processes of black band disease in corals through integrated genomics

Sato, Yui, Ling, Edmund Y. S., Turaev, Dmitrij, Laffy, Patrick, Weynberg, Karen D., Rattei, Thomas, Willis, Bette L. and Bourne, David G. (2017) Unraveling the microbial processes of black band disease in corals through integrated genomics. Scientific Reports, 7 . doi:10.1038/srep40455


Author Sato, Yui
Ling, Edmund Y. S.
Turaev, Dmitrij
Laffy, Patrick
Weynberg, Karen D.
Rattei, Thomas
Willis, Bette L.
Bourne, David G.
Title Unraveling the microbial processes of black band disease in corals through integrated genomics
Journal name Scientific Reports   Check publisher's open access policy
ISSN 2045-2322
Publication date 2017-01-17
Sub-type Article (original research)
DOI 10.1038/srep40455
Open Access Status DOI
Volume 7
Total pages 14
Place of publication London, United Kingdom
Publisher Nature Publishing Group
Language eng
Formatted abstract
Coral disease outbreaks contribute to the ongoing degradation of reef ecosystems, however, microbial mechanisms underlying the onset and progression of most coral diseases are poorly understood. Black band disease (BBD) manifests as a cyanobacterial-dominated microbial mat that destroys coral tissues as it rapidly spreads over coral colonies. To elucidate BBD pathogenesis, we apply a comparative metagenomic and metatranscriptomic approach to identify taxonomic and functional changes within microbial lesions during in-situ development of BBD from a comparatively benign stage termed cyanobacterial patches. Results suggest that photosynthetic CO2-fixation in Cyanobacteria substantially enhances productivity of organic matter within the lesion during disease development. Photosynthates appear to subsequently promote sulfide-production by Deltaproteobacteria, facilitating the major virulence factor of BBD. Interestingly, our metagenome-enabled transcriptomic analysis reveals that BBD-Associated cyanobacteria have a putative mechanism that enables them to adapt to higher levels of hydrogen sulfide within lesions, underpinning the pivotal roles of the dominant cyanobacterium within the polymicrobial lesions during the onset of BBD. The current study presents sequence-based evidence derived from whole microbial communities that unravel the mechanism of development and progression of BBD.
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ
Additional Notes Article number 40455

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
School of Agriculture and Food Sciences
 
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