Sarcopenia and post-hospital outcomes in older adults: a longitudinal study

Perez-Zepeda, Mario Ulises, Sgaravatti, Aldo and Dent, Elsa (2017) Sarcopenia and post-hospital outcomes in older adults: a longitudinal study. Archives of Gerontology and Geriatrics, 69 105-109. doi:10.1016/j.archger.2016.10.013

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Author Perez-Zepeda, Mario Ulises
Sgaravatti, Aldo
Dent, Elsa
Title Sarcopenia and post-hospital outcomes in older adults: a longitudinal study
Journal name Archives of Gerontology and Geriatrics   Check publisher's open access policy
ISSN 1872-6976
0167-4943
Publication date 2017-03-01
Year available 2016
Sub-type Article (original research)
DOI 10.1016/j.archger.2016.10.013
Open Access Status File (Author Post-print)
Volume 69
Start page 105
End page 109
Total pages 5
Place of publication E Park, Shannon, Clare Ireland
Publisher Elsevier Ireland
Language eng
Formatted abstract
Introduction: Sarcopenia poses a significant problem for older adults, yet very little is known about this medical condition in the hospital setting. The aims of this hospital-based study were to determine: (i) the prevalence of sarcopenia; (ii) factors associated with sarcopenia; and (iii) the association of sarcopenia with adverse clinical outcomes post-hospitalisation.

Methods: This is a longitudinal analysis of consecutive patients aged ≥70 years admitted to a Geriatric Management and Evaluation Unit (GEMU) ward. Sarcopenia was classified using the European Working Group on Sarcopenia in Older People (EWGSOP) algorithm, which included: handgrip strength, gait speed, and muscle mass using Bioelectrical Impedance Analysis (BIA). Outcomes were assessed at 12-months post-hospital discharge, and included both mortality and admission to a hospital Emergency Department (ED). Kaplan-Meier methods were used to estimate survival, with Cox proportion hazard models then applied. All regression analyses controlled for age, sex, and co-morbidity.

Results: 172 patients (72% female) with a mean (SD) age of 85.2 (6.4) years were included. Sarcopenia was present in 69 (40.1%) of patients. Patients with sarcopenia were twice as likely to die in the 12-months post-hospitalisation (HR, 95% CI = 2.23, 1.15–4.34), but did not have an increased likelihood of ED admission.

Conclusions: Sarcopenia showed an independent association with 12-month post-hospital mortality in older adults. With the new recognition of sarcopenia as a medical condition with its own unique ICD-10-CM code, awareness and diagnosis of sarcopenia in clinical settings is paramount.
Keyword Aged
Muscle mass
Muscle strength
Sarcopenia/complications
Sarcopenia/mortality
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: HERDC Pre-Audit
Centre for Research in Geriatric Medicine Publications
 
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