Obstructive sleep apnoea in children with obesity

Kassim, Rubina, Harris, Margaret-Anne, Leong, Gary M. and Heussler, Helen (2016) Obstructive sleep apnoea in children with obesity. Journal of Paediatrics and Child Health, 52 3: 284-290. doi:10.1111/jpc.13009

Author Kassim, Rubina
Harris, Margaret-Anne
Leong, Gary M.
Heussler, Helen
Title Obstructive sleep apnoea in children with obesity
Journal name Journal of Paediatrics and Child Health   Check publisher's open access policy
ISSN 1440-1754
Publication date 2016-03-01
Year available 2016
Sub-type Article (original research)
DOI 10.1111/jpc.13009
Open Access Status Not yet assessed
Volume 52
Issue 3
Start page 284
End page 290
Total pages 7
Place of publication Chichester, West Sussex United Kingdom
Publisher Wiley-Blackwell Publishing
Language eng
Formatted abstract

The aim of this study was to identify factors that predict risk of obstructive sleep apnoea (OSA) in obese children, which could aid in prioritising sleep studies.


A retrospective chart review was undertaken of obese children seen in the KOALA weight management clinic and Sleep clinic. Data collected included demographics, clinical history, examination findings, biochemical markers, and polysomnogram results.


Two hundred seventy-two obese children were seen in the KOALA clinic out of which 54 (20%) were also seen in the Sleep clinic because of snoring. Thirty-two were referred by the KOALA clinic; the remaining 22 were referred by other medical practitioners prior to being seen in the KOALA clinic. Thirty-nine had polysomnograms. The time from referral to Sleep clinic ranged from 10 days to 1.5 years with 50% seen within 6 months; with similar time gap between the blood tests and time of polysomnograms. Thirty-six percent (14/39) were reported to have OSA. Six children were Aboriginal/Torres Strait Islander (ATSI) and all had OSA, which was statistically significant (P = 0.004). There was a statistically significant correlation between high-sensitivity C-reactive protein (hs-CRP) and obstructive event index (OEI) in rapid eye movement (REM) sleep. (r = 0.50, P = 0.04). Correlation between low-density lipoprotein (LDL) and OEI in REM was r = 0.36, P = 0.06, which approached significance.


Ethnicity was a significant factor with more obese ATSI children having OSA. The significant correlation between hs-CRP with OEI is consistent with findings of previous studies. Several factors (glycosylated haemoglobin, LDL) approached significance.
Keyword Child
Sleep apnoea
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ
Additional Notes PMCID: 26748912

Document type: Journal Article
Sub-type: Article (original research)
Collections: Mater Research Institute-UQ (MRI-UQ)
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Created: Mon, 12 Dec 2016, 20:30:50 EST by Julia McCabe on behalf of Mater Research Institute-UQ